Evidence map›Paper›PMID 31685460›Full record

ArticleAntimicrobial agents and chemotherapy2019

The Transcriptional Repressor SmvR Is Important for Decreased Chlorhexidine Susceptibility in Enterobacter cloacae Complex.

François Guérin, François Gravey, Patrick Plésiat, Marion Aubourg, Racha Beyrouthy, Richard Bonnet, Vincent Cattoir, Jean-Christophe Giard

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Highly Effective Biocides againstACS infectious diseases · 2024
    Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

François GuérinNormandie University, UNICAEN, UNIROUEN, GRAM 2.0, Caen, France guerin-f@chu-caen.fr.
François GraveyNormandie University, UNICAEN, UNIROUEN, GRAM 2.0, Caen, France.
Patrick PlésiatCentre National de Référence de la Résistance aux Antibiotiques, Centre Hospitalier Universitaire de Besançon, Besançon, France.ORCID 0000-0001-7381-5671
Marion AubourgUniversity of Caen Normandie, Unité de Recherche Risques Microbiens (U2RM), Caen, France.
Racha BeyrouthyClermont-Ferrand, University Hospital, Department of Clinical Microbiology, Clermont-Ferrand, France.
Richard BonnetClermont-Ferrand, University Hospital, Department of Clinical Microbiology, Clermont-Ferrand, France.
Vincent CattoirRennes University Hospital, Department of Clinical Microbiology and CNR de la Résistance aux Antibiotiques, Rennes, France.ORCID 0000-0003-4026-9912
Jean-Christophe GiardUniversity of Caen Normandie, Unité de Recherche Risques Microbiens (U2RM), Caen, France.
Centre Hospitalier Universitaire de Clermont-Ferrand · FRNormandie Université · FRUniversité de Caen Normandie · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major facilitator superfamily (MFS) efflux pumps have been shown to be important for bacterial cells to cope with biocides such as chlorhexidine (CHX), a widely used molecule in hospital settings. In this work, we evaluated the role of two genes,

Indexed as

Anti-Bacterial AgentsBacterial ProteinsChlorhexidineComputational BiologyEnterobacter cloacaeMicrobial Sensitivity TestsOpen Reading FramesReverse Transcriptase Polymerase Chain ReactionWhole Genome SequencingAnti-Bacterial AgentsBacterial ProteinsChlorhexidinechlorhexidineECCE. cloacaeeffluxMFS

Identifiers

PMID31685460
PMCPMC7187565
OpenAlexW2982553676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.