Evidence map›Paper›PMID 31685458›Full record

ArticleAntimicrobial agents and chemotherapy2019

What's Old Is New Again: Bacteriophage Therapy in the 21st Century.

Saima Aslam, Robert T Schooley

Abstract readComment
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Safety Properties ofFoods (Basel, Switzerland) · 2023
    Review
  4. Article
  5. Phage therapeutics: from promises to practices and prospectives.Applied microbiology and biotechnology · 2021
    Review
  6. Review
  7. Bacteriophage Cocktails Protect Dairy Cows Against Mastitis Caused By Drug ResistantFrontiers in cellular and infection microbiology · 2021
    Article
  8. Phage Therapy: Towards a Successful Clinical Trial.Antibiotics (Basel, Switzerland) · 2020
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Saima AslamDivision of Infectious Diseases and Global Public Health, Center for Innovative Phage Applications and Therapeutics, University of California, San Diego, San Diego, California saslam@ucsd.edu.
Robert T SchooleyDivision of Infectious Diseases and Global Public Health, Center for Innovative Phage Applications and Therapeutics, University of California, San Diego, San Diego, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We highlight features associated with bacteriophage therapy that make it an attractive treatment option for multidrug-resistant infections and also discuss some of the challenges that need to be considered in the design and execution of clinical trials directed at evaluating the efficacy of bacteriophage therapy in humans.

Indexed as

BacteriophagesPhage TherapyProsthesis-Related InfectionsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansPseudomonas aeruginosaAnti-Bacterial Agentsantimicrobial resistance (AMR)bacteriophage therapymultidrug resistance (MDR)phage therapy

Identifiers

PMID31685458
PMCPMC7187564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.