Evidence map›Paper›PMID 31685441›Full record

ArticleSleep health2020

Excessive sleepiness and associated symptoms in the U.S. adult population: prevalence, correlates, and comorbidity.

Bhanu Prakash Kolla, Jian-Ping He, Meghna P Mansukhani, Mark A Frye, Kathleen Merikangas

Open access · greenAbstract read
In one paragraph

Article in Sleep health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  6. Idiopathic hypersomnia is a 24-hour disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
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  8. Subjective daytime sleepiness, not sleep quality or hypoxia, predicts sleep-dependent memory consolidation in a cohort of older adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  9. Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  10. Sleep health of adults and children with Moebius syndrome.Research in developmental disabilities · 2025
    Article
  11. Article
  12. Review
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  16. Review
  17. Article
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  19. Socioeconomic status and sleep health: a narrative synthesis of 3 decades of empirical research.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bhanu Prakash KollaDepartment of Psychiatry and Psychology Mayo Clinic, Rochester, MN; Center for Sleep Medicine Mayo Clinic, Rochester, MN. Electronic address: kolla.bhanuprakash@mayo.edu.
Jian-Ping HeNational Institute of Mental Health Intramural Research Program, Genetic Epidemiology Research Branch, Bethesda, MD.
Meghna P MansukhaniCenter for Sleep Medicine Mayo Clinic, Rochester, MN.
Mark A FryeDepartment of Psychiatry and Psychology Mayo Clinic, Rochester, MN.
Kathleen MerikangasNational Institute of Mental Health Intramural Research Program, Genetic Epidemiology Research Branch, Bethesda, MD.
Mayo Clinic in Arizona · USNational Institute of Mental Health · USMayo Clinic · US

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Population-Based Epidemiologic ResearchZIAMH002953 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2016 to 2025
$7.0M
National Comorbidity Survey - Adolescent (NCS-A)ZIAMH002808 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2009 to 2015
$3.2M
Intramural NIH HHS ZIA MH002808NIMH NIH HHS U01 MH060220
6 · The paper itself

Abstract

objectiveThis study examined the prevalence, sociodemographic features, patterns of comorbidity, and impact on functional impairment of excessive sleepiness (Ex.S) and associated symptoms in a nationally representative sample of adults using the National Comorbidity Survey Replication (NCS-R) dataset.

methodsParticipants ≥18 years (n = 5,962) were queried about their sleep using the Composite International Diagnostic Interview (CIDI). Specifically, respondents were questioned about feeling sleepy during the day and falling asleep in permissive situations, feelings of insufficient sleep despite adequate time in bed, and/or difficulty waking up. Those endorsing daytime sleepiness and at least one additional symptom were considered to have Ex.S plus associated symptoms. Associations between Ex.S plus associated symptoms and sociodemographics, Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) mental disorders, chronic physical conditions, and functional impairment were examined.

resultsThe prevalence of Ex.S plus associated symptoms in U.S. adults was 23.34% (standard error [SE] = 0.88) and significantly co-occurred with insomnia-related symptoms after adjusting for confounders (Odds ratio [OR] = 5.65; 95% confidence interval [CI] = 4.55-7.02). The presence of Ex.S and associated symptoms was more common in women, particularly younger women, those with lower family income, and the unemployed (all P<.001). After controlling for demographic characteristics and other confounders, Ex.S plus associated symptoms was associated with having a DSM-IV mental disorder (OR = 4.25; 95% CI = 3.53-5.10), a chronic physical condition (OR = 2.57; 95% CI = 1.94-3.42) and greater disability (P<.001).

conclusionEx. S with associated symptoms was common, frequently co-occurred with other mental and physical conditions, and was associated with substantial disability. Dissipation of some associations after controlling for insomnia-related symptoms indicated that physical-mental comorbidity and disability were greater among individuals with more pervasive sleep disturbances.

Indexed as

AdolescentAdultAgedAged, 80 and overComorbidityDisorders of Excessive SomnolenceFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceRisk FactorsUnited StatesYoung AdultComorbidityExcessive sleepinessFunctional impairmentHypersomnolenceInsomnia

Identifiers

PMID31685441
PMCPMC8922410
OpenAlexW2985572185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.