Evidence map›Paper›PMID 31685398›Full record

ReviewJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2020

Interplay between host-microbe and microbe-microbe interactions in cystic fibrosis.

Catherine R Armbruster, Tom Coenye, Lhousseine Touqui, Jennifer M Bomberger

Abstract readReview
In one paragraph

Review in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Role of Iron Availability in ModulatingJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Biofilm Formation byInternational journal of molecular sciences · 2022
    Review
  14. Article
  15. Biofilm aggregates and the host airway-microbial interface.Frontiers in cellular and infection microbiology · 2022
    Review
  16. Characterization of theFrontiers in cellular and infection microbiology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine R ArmbrusterMicrobiology and Molecular Genetics, University of Pittsburgh, United States. Electronic address: c4therine@pitt.edu.
Tom CoenyeLaboratory of Pharmaceutical Microbiology, Ghent University, Belgium.
Lhousseine TouquiCystic Fibrosis: Physiopathology and Phenogenomics, CRSA Pasteur Institute and Hôpital Saint-Antoine, France.
Jennifer M BombergerMicrobiology and Molecular Genetics, University of Pittsburgh, United States.

Funding

Pittsburgh Training Grant in Pediatric Pulmonary MedicineT32HL129949 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Juan Carlos Celedon · 2016 to 2026
$2.9M
Impact of Virome on Microbial Communities in the Respiratory TractR33HL137077 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOMBERGER, JENNIFER MELINDA · 2019 to 2021
$2.2M
Polymicrobial Interactions in the Respiratory TractR01HL142587 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOMBERGER, JENNIFER MELINDA · 2019 to 2022
$1.6M
Viral-bacterial co-infections in the lungR01HL123771 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOMBERGER, JENNIFER MELINDA · 2015 to 2018
$1.5M
Impact of virome on microbial communities in the respiratory tractR61HL137077 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOMBERGER, JENNIFER MELINDA · 2017 to 2018
$524k
NHLBI NIH HHS R01 HL123771NHLBI NIH HHS R01 HL142587NHLBI NIH HHS R33 HL137077NHLBI NIH HHS R61 HL137077NHLBI NIH HHS T32 HL129949
6 · The paper itself

Abstract

The respiratory tract of individuals with cystic fibrosis is host to polymicrobial infections that persist for decades and lead to significant morbidity and mortality. Improving our understanding of CF respiratory infections requires coordinated efforts from researchers in the fields of microbial physiology, genomics, and ecology, as well as epithelial biology and immunology. Here, we have highlighted examples from recent CF microbial pathogenesis literature of how the host nutritional environment, immune response, and microbe-microbe interactions can feedback onto each other, leading to diverse effects on lung disease pathogenesis in CF.

Indexed as

Cystic FibrosisHost-Pathogen InteractionsMicrobial InteractionsRespiratory Tract InfectionsAnti-Infective AgentsCoinfectionHumansRespiratory SystemAnti-Infective AgentsAntimicrobial resistanceBiofilmInfectionLungPathogenesisPolymicrobial

Identifiers

PMID31685398
PMCPMC7035965

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.