Observational studyAnnals of emergency medicine2020
Opioid Use During the Six Months After an Emergency Department Visit for Acute Pain: A Prospective Cohort Study.
Observational study in Annals of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Pooled it
- A Systematic Review of Pain Management Education in Graduate Medical Education.Journal of graduate medical education · 2022Pooled it
- Perceptions of Signs of Addiction Among Opioid Naive Patients Prescribed Opioids in the Emergency Department.Journal of addiction medicineTrial
- Association of acute opioid-induced euphoria and analgesia with subsequent opioid prescriptions in an emergency department-based prospective cohort study.Clinical and experimental emergency medicine · 2026Article
- Optimizing deprescribing of hospital-initiated opioids: a multi-level consensus study bridging evidence, expertise, and patient perspectives.Scientific reports · 2025Article
- A Prospective Cohort Study to Determine Which Opioid-Naïve Emergency Department Patients Are at Risk of Persistent Opioid Use.Annals of emergency medicine · 2025Article
- Limited use of opioid prescribing guidelines in Dutch emergency departments: results of a nationwide survey.International journal of emergency medicine · 2024Article
- An updated view on the influence of initial opioid prescription characteristics on long-term opioid use among opioid naïve patients.Drug and alcohol dependence · 2024Article
- Frequency of Persistent Opioid Use 6 Months After Exposure to IV Opioids in the Emergency Department: A Prospective Cohort Study.The Journal of emergency medicine · 2024Observational
- The association between specific narrative elements and patient perspectives on acute pain treatment.The American journal of emergency medicine · 2023Article
- Use of clinical phenotypes to characterize emergency department patients administered intravenous opioids for acute pain.Clinical and experimental emergency medicine · 2023Article
- Variation in prescribing of opioids for emergency department encounters: A cohort study in the Military Health System.Journal of evaluation in clinical practice · 2022Article
- Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study.PloS one · 2022Article
- Association between 1-year patient outcomes and opioid-prescribing group of emergency department clinicians: A cohort study with Army active-duty soldiers.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021Article
- Impact of a Mandatory Prescription Drug Monitoring Program Check on Emergency Department Opioid Prescribing Rates.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021Article
- Incidence of opioid use disorder in the year after discharge from an emergency department encounter.Journal of the American College of Emergency Physicians open · 2021Article
- Predicting the Transition to Chronic Pain 6 Months After an Emergency Department Visit for Acute Pain: A Prospective Cohort Study.The Journal of emergency medicine · 2020Observational
- Association of Emergency Department Opioid Administration With Ongoing Opioid Use: A Retrospective Cohort Study of Patients With Back Pain.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2020Article
- New persistent opioid use after acute opioid prescribing in pregnancy: a nationwide analysis.American journal of obstetrics and gynecology · 2020Article
Corrections and comments
- Commented on by
- Commented on byIn reply.2020
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
STUDY
objectiveDespite the frequent use of opioids to treat acute pain, the long-term risks and analgesic benefits of an opioid prescription for an individual emergency department (ED) patient with acute pain are still poorly understood and inadequately quantified. Our objective was to determine the frequency of recurrent or persistent opioid use during the 6 months after the ED visit
methodsThis was a prospective, observational cohort study of opioid-naive patients presenting to 2 EDs for acute pain who were prescribed an opioid at discharge. Patients were followed by telephone 6 months after the ED visit. Additionally, we reviewed the statewide prescription monitoring program database. Outcomes included frequency of recurrent and persistent opioid use and frequency of persistent moderate or severe pain 6 months after the ED visit. Persistent opioid use was defined as filling greater than or equal to 6 prescriptions during the 6-month study period.
resultsDuring 9 months beginning in November 2017, 733 patients were approached for participation. Four hundred eighty-four met inclusion criteria and consented to participate. Four hundred ten patients (85%) provided 6-month telephone data. The prescription monitoring database was reviewed for all 484 patients (100%). Most patients (317/484, 66%; 95% confidence interval 61% to 70%) filled only the initial prescription they received in the ED. One in 5 patients (102/484, 21%; 95% confidence interval 18% to 25%) filled at least 2 prescriptions within the 6-month period. Five patients (1%; 95% confidence interval 0% to 2%) met criteria for persistent opioid use. Of these 5 patients, all but 1 reported moderate or severe pain in the affected body part 6 months later.
conclusionAlthough 1 in 5 opioid-naive ED patients who received an opioid prescription for acute pain on ED discharge filled at least 2 opioid prescriptions in 6 months, only 1% had persistent opioid use. These patients with persistent opioid use were likely to report moderate or severe pain 6 months after the ED visit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.