Evidence map›Paper›PMID 31685232›Full record

ArticleGynecologic oncology2020

Radiomic features of cervical cancer on T2-and diffusion-weighted MRI: Prognostic value in low-volume tumors suitable for trachelectomy.

Benjamin W Wormald, Simon J Doran, Thomas Ej Ind, James D'Arcy, James Petts, Nandita M deSouza

Open access · hybridAbstract read
In one paragraph

Article in Gynecologic oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

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  16. Radiomics in surgical oncology: applications and challenges.Computer assisted surgery (Abingdon, England) · 2021
    Review
  17. Radiomics in cervical and endometrial cancer.The British journal of radiology · 2021
    Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin W WormaldMRI Unit, Division of Radiotherapy and Imaging, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, Sutton, UK.
Simon J DoranMRI Unit, Division of Radiotherapy and Imaging, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, Sutton, UK.
Thomas Ej IndDepartment of Gynaecological Oncology, The Royal Marsden NHS Foundation Trust, London, UK; St George's University of London, Tooting, London, UK.
James D'ArcyMRI Unit, Division of Radiotherapy and Imaging, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, Sutton, UK.
James PettsMRI Unit, Division of Radiotherapy and Imaging, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, Sutton, UK.
Nandita M deSouzaMRI Unit, Division of Radiotherapy and Imaging, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: nandita.desouza@icr.ac.uk.
Royal Marsden NHS Foundation Trust · GBInstitute of Cancer Research · GBSt George's, University of London · GB

Funding

Cancer Research UK 16464Cancer Research UK C1060/A10334Cancer Research UK C1060/A16464Cancer Research UK C7273/A28677Department of HealthMedical Research Council G0802470
6 · The paper itself

Abstract

backgroundTextural features extracted from MRI potentially provide prognostic information additional to volume for influencing surgical management of cervical cancer. PURPOSE: To identify textural features that differ between cervical tumors above and below the volume threshold of eligibility for trachelectomy and determine their value in predicting recurrence in patients with low-volume tumors.

methodsOf 378 patients with Stage1-2 cervical cancer imaged prospectively (3T, endovaginal coil), 125 had well-defined, histologically-confirmed squamous or adenocarcinomas with >100 voxels (>0.07 cm

resultsTextural features (Dissimilarity, Energy, ClusterProminence, ClusterShade, InverseVariance, Autocorrelation) in 6 of 10 clusters from T2-W and ADC data differed between high-volume (mean ± SD 15.3 ± 11.7 cm

conclusionTextural features from ADC maps and T2-W images differ between high- and low-volume tumors and potentially predict recurrence in low-volume tumors.

Indexed as

AdultAgedAged, 80 and overDiffusion Magnetic Resonance ImagingFemaleHumansLogistic ModelsMiddle AgedNeoplasm StagingPilot ProjectsPrognosisProspective StudiesTrachelectomyTumor BurdenUterine Cervical NeoplasmsYoung AdultCervical cancerMRIRadiomicsRecurrenceTrachelectomy

Identifiers

PMID31685232
PMCPMC7001101
OpenAlexW2985418136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.