ArticleNutrition journal2019
Does the inflammatory potential of diet affect disease activity in patients with inflammatory bowel disease?
Article in Nutrition journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Relationship between diet quality and inflammatory bowel disease: a systematic review of observational studies.BMC gastroenterology · 2025Pooled it
- Epidemiologic profile of inflammatory bowel disease in Eastern Mediterranean Region (EMRO) countries: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Pooled it
- Index-Based Dietary Patterns and Inflammatory Bowel Disease: A Systematic Review of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Pooled it
- Regulatory mechanism of the RNF168-SCCA1-MYH9 signaling axis in the response of ulcerative colitis.Journal of gastroenterology · 2026Article
- Dietary inflammatory index and objective disease activity in IBD: no association found.European journal of clinical nutrition · 2026Observational
- The Association between Empirical Dietary Inflammatory Pattern and Disease Activity and Quality of Life in Patients with Inflammatory Bowel Disease: A Cross-Sectional Study.International journal of preventive medicine · 2026Article
- The risk of infertility and dietary inflammatory index, a case-control study in Iran.Archives of gynecology and obstetrics · 2025Article
- Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis.Journal of advanced research · 2025Article
- Association Between Pro-Inflammatory Potential of Diet and Inflammatory Parameters in a Group of Patients with Inflammatory Bowel Disease.Nutrients · 2025Article
- Dietary inflammatory potential, genetic predisposition, and incidence of Crohn's disease and ulcerative colitis.Nutrition & metabolism · 2025Article
- Dietary Relationships between Obesity and Inflammatory Bowel Diseases: A Narrative Review of Diets Which May Promote Both Diseases.Current gastroenterology reports · 2025Review
- Association between dietary inflammatory index and phase angle in university employees: a cross-sectional study.Scientific reports · 2024Article
- Association between dietary inflammatory index and disease activity in patients with ulcerative colitis.Scientific reports · 2024Article
- Use of Treatment and Self-Management Methods: Perspectives and Decisions of Patients With Ulcerative Colitis.American journal of lifestyle medicine · 2024Article
- Ulcerative Colitis Is Associated With Diet-related Inflammation and Physical Activity in the IBD Partners E-cohort.Inflammatory bowel diseases · 2024Article
- Low Emulsifier Diet in Healthy Female Adults: A Feasibility Study of Nutrition Education and Counseling Intervention.Healthcare (Basel, Switzerland) · 2023Article
- Pro-Inflammatory Diet Is Correlated with HighNutrients · 2023Article
- Evaluating macro- and micronutrients and food groups intake with the risk of developing inflammatory bowel disease: Is there any association?Food science & nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiet is an important modulator of inflammation, which is associated with inflammatory bowel disease (IBD). In this study, we examined whether the inflammatory properties of diets are associated with disease activity in patients with IBD.
methodsA cross-sectional study was conducted on 143 IBD patients, including 32 patients with Crohn's disease (CD) and 111 patients with ulcerative colitis (UC). Dietary intakes were assessed by a valid 168-item food frequency questionnaire (FFQ). The inflammatory potential of the diet was assessed by calculating the two scores of Dietary Inflammatory Index (DII®), and the Empirical Dietary Inflammatory Pattern (EDIP), and CD and UC disease activity were determined by the Crohn's disease activity index (CDAI) and the Mayo score, respectively. Associations of the inflammatory indices as median and as tertiles with disease activity were analyzed using logistic regression in a univariate model and after adjusting for total energy intake (continuous), type of disease (CD and UC) and drug consumption (no drugs, single drug, and multiple drugs).
resultsSixty-four IBD patients (44.8%) in this study had active disease.The DII® score and the EDIP did not differ significantly between active and inactive patients (- 1.45 ± 1.04 vs.- 1.20 ± 1.24; 0.56 ± 0.22 vs. 0.53 ± 0.28, respectively). After adjusting for energy intake, drug use, and IBD type, the odds (95%CIs) of active disease among patients in tertile 3 compared to those in tertile 1 were 0.84 (0.32-2.17) for DII and 1.50 (0.61-3.72) for EDIP; neither of which were statistically significantly different from the rates in tertile 1.
conclusionsAlthough point estimates were in the expected direction of increased risk, the inflammatory potential of diet, assessed using DII or EDIP, was not associated with severity of disease in IBD patients. Whether diet-related inflammation affects disease activity in patients with IBD deserves further investigations.
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