Evidence map›Paper›PMID 31684938›Full record

ArticleBMC health services research2019

The structure of the quality of clinical practice guidelines with the items and overall assessment in AGREE II: a regression analysis.

Yosuke Hatakeyama, Kanako Seto, Rebeka Amin, Takefumi Kitazawa, Shigeru Fujita, Kunichika Matsumoto, Tomonori Hasegawa

Abstract read
In one paragraph

Article in BMC health services research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yosuke HatakeyamaDepartment of Social Medicine, Toho University School of Medicine, 5-21-16, Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan.
Kanako SetoDepartment of Social Medicine, Toho University School of Medicine, 5-21-16, Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan.
Rebeka AminDepartment of Social Medicine, Toho University Graduate School of Medicine, Tokyo, Japan.
Takefumi KitazawaFaculty of Health Sciences, Tokyo Kasei University, Saitama, Japan.
Shigeru FujitaDepartment of Social Medicine, Toho University School of Medicine, 5-21-16, Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan.
Kunichika MatsumotoDepartment of Social Medicine, Toho University School of Medicine, 5-21-16, Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan.
Tomonori HasegawaDepartment of Social Medicine, Toho University School of Medicine, 5-21-16, Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan. health@med.toho-u.ac.jp.ORCID http://orcid.org/0000-0002-1057-9867

Funding

Japanese Ministry of Health, Labor, and Welfare H14-Iryo-035Japanese Ministry of Health, Labor, and Welfare H17-Iryo Ippan-041Japanese Ministry of Health, Labor, and Welfare H20-Iryo Ippan-027Japanese Ministry of Health, Labor, and Welfare H24-Iryo Ippan-020
6 · The paper itself

Abstract

backgroundThe Appraisal of Guidelines for Research & Evaluation (AGREE) II has been widely used to evaluate the quality of clinical practice guidelines (CPGs). While the relationship between the overall assessment of CPGs and scores of six domains were reported in previous studies, the relationship between items constituting these domains and the overall assessment has not been analyzed. This study aims to investigate the relationship between the score of each item and the overall assessment and identify items that could influence the overall assessment.

methodsAll Japanese CPGs developed using the evidence-based medicine method and published from 2011 to 2015 were used. They were independently evaluated by three appraisers using AGREE II. The evaluation results were analyzed using regression analysis to evaluate the influence of 6 domains and 23 items on the overall assessment.

resultsA total of 206 CPGs were obtained. All domains and all items except one were significantly correlated to the overall assessment. Regression analysis revealed that Domain 3 (Rigour of Development), Domain 4 (Clarity of Presentation), Domain 5 (Applicability), and Domain 6 (Editorial Independence) had influence on the overall assessment. Additionally, four items of AGREE II, clear selection of evidence (Item 8), specific/unambiguous recommendations (Item 15), advice/tools for implementing recommendations (Item 19), and conflicts of interest (Item 22), significantly influenced the overall assessment and explained 72.1% of the variance.

conclusionsThese four items may highlight the areas for improvement in developing CPGs.

Indexed as

Evidence-Based MedicineHumansPractice Guidelines as TopicRegression AnalysisAGREEAppraisalPractice guidelinePractice guidelines as topicQuality

Identifiers

PMID31684938
PMCPMC6827207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.