Evidence map›Paper›PMID 31684829›Full record

ArticleTechnology in cancer research & treatment

Long Noncoding RNA GM16343 Promotes IL-36β to Regulate Tumor Microenvironment by CD8

Deli Mao, Chenrui Hu, Jianglei Zhang, Chao Feng, Zhe Zhang, Jin Wang, Zhongsong Man, Zhongwei Zhu, Yunliang Wang, Hua Zhao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. IL-36β promotes anti-tumor effects in CD8Annals of translational medicine · 2021
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Long noncoding RNA: a dazzling dancer in tumor immune microenvironment.Journal of experimental & clinical cancer research : CR · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Deli MaoDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-5430-0883
Chenrui HuDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jianglei ZhangDepartment of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chao FengSoochow University Institutes for Translational Medicine, Suzhou, China.
Zhe ZhangDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jin WangDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-4334-3228
Zhongsong ManDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhongwei ZhuDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yunliang WangDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hua ZhaoDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xinguo ZhuDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jun OuyangDepartment of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xiaoqiang DongDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xin ZhaoDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-5570-6690
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of long noncoding RNA GM16343 on interleukin 36β promotion of CD8

methodsThe differentially expressed long noncoding RNA in interleukin 36β-stimulated mouse CD8

resultsA total of 12 long noncoding RNAs with significant differences were screened by gene chip analysis. Real-time polymerase chain reaction showed that the difference in GM16343 was larger, and the difference between the groups was observed to be the most significant. Compared to control group, CD8

conclusionInterleukin 36β may enhance antitumor immune response of CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCell ProliferationCells, CulturedComputational BiologyDisease Models, AnimalGene Expression ProfilingGene Expression Regulation, NeoplasticGene Knockout TechniquesInterleukin-1MiceNeoplasmsRNA InterferenceRNA, Long NoncodingRNA, Small InterferingTumor BurdenInterleukin-1RNA, Long NoncodingRNA, Small Interferingcolorectal cancerGM16343IL-36βlncRNAtumor immunitytumor microenvironment

Identifiers

PMID31684829
PMCPMC6831968
OpenAlexW2987221722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.