Evidence map›Paper›PMID 31684059›Full record

ArticleVaccines2019

Recombinant

Li Wang, Tian Xia, Tiantian Guo, Yi Ru, Yanping Jiang, Wen Cui, Han Zhou, Xinyuan Qiao, Lijie Tang, Yigang Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Characterisation ofInternational journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Li WangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. wanglicau@163.com.
Tian XiaCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. 13206521680@163.com.
Tiantian GuoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. 15645171752@163.com.
Yi RuState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China. ruyi@caas.cn.
Yanping JiangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. jiangyanping2017@126.com.
Wen CuiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. cuiwen_200@163.com.
Han ZhouCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. zhouhan9659@163.com.
Xinyuan QiaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. qiaoxinyuan@126.com.
Lijie TangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. tanglijie@neau.edu.cn.
Yigang XuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. yigangxu_china@sohu.com.
Yijing LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. yijingli@163.com.
Northeast Agricultural University · CNChinese Academy of Agricultural Sciences · CN

Funding

National Key R&D Program of China 2017YFD0501105National Natural Science Foundation of China 31702260State Key Laboratory of Veterinary Etiological Biology SKLVEB2018KFKT004University Nursing Program for Yong Scholars with Creative Talents in Heilongjiang Province UNPYSCT-2018147
6 · The paper itself

Abstract

Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging, liver necrosis, and high morbidity and mortality in rabbits and hares, causes severe economic losses in the rabbit industry worldwide. Due to the lack of an efficient in-vitro propagation system for RHDV, the current vaccine is produced via chemical inactivation of crude RHDV preparation derived from the livers of infected rabbits. Inactivated vaccines are effective for controlling RHD, but the potential problems of biosafety and animal welfare have negative effects on the application of inactivated vaccines. In this study, an oral Lactobacillus casei (

Indexed as

Lactobacillus casei (L. casei)rabbit hemorrhagic disease virus (RHDV)vaccineVP60(VP1)

Identifiers

PMID31684059
PMCPMC6963290
OpenAlexW2986160701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.