Evidence map›Paper›PMID 31683965›Full record

ArticleInternational journal of molecular sciences2019

Targeted Delivery Prodigiosin to Choriocarcinoma by Peptide-Guided Dendrigraft Poly-l-lysines Nanoparticles.

Kai Zhao, Dan Li, Guogang Cheng, Baozhen Zhang, Jinyu Han, Jie Chen, Baobei Wang, Mengxia Li, Tianxia Xiao, Jian Zhang and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Promising Prodiginins Biological Activities.Chemistry & biodiversity · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Selective Cytotoxic Activity of Prodigiosin@halloysite Nanoformulation.Frontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kai ZhaoEngineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China. zybin395@126.com.ORCID 0000-0001-6139-1912
Dan LiEngineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China. docor1005@163.com.
Guogang ChengKey Laboratory of Microbiology, College of Heilongjiang Province, School of Life Science, Heilongjiang University, Harbin 150080, China. gangzi350274360@126.com.
Baozhen ZhangGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. bz.zhang2@siat.ac.cn.
Jinyu HanKey Laboratory of Microbiology, College of Heilongjiang Province, School of Life Science, Heilongjiang University, Harbin 150080, China. jy.han1@siat.ac.cn.
Jie ChenGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. jie.chen@siat.ac.cn.ORCID 0000-0001-8732-4048
Baobei WangGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. bb.wang@siat.ac.cn.
Mengxia LiGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. limx@siat.ac.cn.
Tianxia XiaoGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. tx.xiao@siat.ac.cn.
Jian ZhangGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. jian.zhang@siat.ac.cn.
Dongpo ZhouEngineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China. zhoudp0451@163.com.
Zheng JinKey Laboratory of Chemical Engineering Process and Technology for High-efficiency Conversion, College of Chemistry and Material Sciences, Heilongjiang University, Harbin 150080, China. jinzhengdvd@163.com.
Xiujun FanGuangdong Key Laboratory of Nanomedicine, Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518052, China. xj.fan@telomerescitech.com.ORCID 0000-0003-3322-1857
Chinese Academy of Sciences · CNHeilongjiang University · CN

Funding

Excellent Youth Natural Science Foundation of Heilongjiang Province of China JC2018008National Key Research and Development Program of China 2016YFC1000402National Natural Science Foundation of China 81571445, 81771617, 31771000Natural Science Foundation of Guangdong Province 2016A030313178Shenzhen Basic Research Fund JCYJ20170413165233512Technological Innovation Talent of Special Funds for Outstanding Subject Leaders in Harbin 2017RAXXJ001
6 · The paper itself

Abstract

The available and effective therapeutic means to treat choriocarcinoma is seriously lacking, mainly due to the toxic effects caused by chemotherapy and radiotherapy. Accordingly, we developed a method for targeting delivery of chemotherapeutical drugs only to cancer cells, not normal cells,

Indexed as

Antineoplastic AgentsApoptosisCell Line, TumorChondroitin SulfatesChoriocarcinomaDrug CompoundingDrug Delivery SystemsDrug LiberationHumansNanoparticlesPeptidesPolylysineProdigiosinReproducibility of ResultsAntineoplastic AgentsChondroitin SulfatesPeptidesPolylysineProdigiosinchoriocarcinomadendrigraft poly-l-lysines nanoparticlesplacenta chondroitin sulfate A binding peptideSerratia marcescens prodigiosintargeted delivery

Identifiers

PMID31683965
PMCPMC6862698
OpenAlexW2984507489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.