Evidence map›Paper›PMID 31683836›Full record

ReviewInternational journal of environmental research and public health2019

Revisiting John Snow to Meet the Challenge of Nontuberculous Mycobacterial Lung Disease.

Aashka Parikh, Christopher Vinnard, Nicole Fahrenfeld, Amy L Davidow, Amee Patrawalla, Alfred Lardizabal, Andrew Gow, Reynold Panettieri, Maria Gennaro

Open access · goldAbstract readHistorical ArticleReview
In one paragraph

Review in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. The respiratory microbiome and nontuberculous mycobacteria: an emerging concern in human health.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Aashka ParikhNew Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA. app101@njms.rutgers.edu.
Christopher VinnardPublic Health Research Institute, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA. christopher.vinnard@njms.rutgers.edu.
Nicole FahrenfeldSchool of Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. nfahrenf@rutgers.edu.ORCID 0000-0003-2690-0122
Amy L DavidowSchool of Public Health, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA. davidoal@sph.rutgers.edu.
Amee PatrawallaNew Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA. patrawam@njms.rutgers.edu.
Alfred LardizabalNew Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA. lardizaa@njms.rutgers.edu.
Andrew GowErnest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. gow@pharmacy.rutgers.edu.
Reynold PanettieriRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA. rp856@rbhs.rutgers.edu.
Maria GennaroPublic Health Research Institute, Rutgers, The State University of New Jersey, Newark, NJ 07103, USA. gennarma@njms.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Foam cells as drug targets in tuberculosisR01HL149450 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GENNARO, MARIA LAURA, KARAKOUSIS, PETROS C · 2019 to 2022
$3.9M
NO-Modified Biomolecules and Pulmonary SignalingR01HL086621 · NHLBI · RUTGERS, THE STATE UNIV OF N.J. · PI GOW, ANDREW J · 2008 to 2016
$2.8M
Rifampicin Malabsorption in HIV+ Patients: Mechanisms and Recovery after HAARTK23AI102639 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VINNARD, CHRISTOPHER · 2014 to 2018
$695k
National Institute of Allergy and Infectious Diseases 1K23AI102639-06NHLBI NIH HHS R01 HL086621NHLBI NIH HHS R01 HL149450
6 · The paper itself

Abstract

Nontuberculous mycobacteria (NTM) are ubiquitous components of the soil and surface water microbiome. Disparities by sex, age, and geography demonstrate that both host and environmental factors are key determinants of NTM disease in populations, which predominates in the form of chronic pulmonary disease. As the incidence of NTM pulmonary disease rises across the United States, it becomes increasingly evident that addressing this emerging human health issue requires a bold, multi-disciplinary research framework that incorporates host risk factors for NTM pulmonary disease alongside the determinants of NTM residence in the environment. Such a framework should include the assessment of environmental characteristics promoting NTM growth in soil and surface water, detailed evaluations of water distribution systems, direct sampling of water sources for NTM contamination and species diversity, and studies of host and bacterial factors involved in NTM pathogenesis. This comprehensive approach can identify intervention points to interrupt the transmission of pathogenic NTM species from the environment to the susceptible host and to reduce NTM pulmonary disease incidence.

Indexed as

Disease OutbreaksHistory, 19th CenturyHistory, 20th CenturyHistory, 21st CenturyHumansIncidenceLung DiseasesMycobacterium Infections, NontuberculousRespiratory Tract InfectionsTopography, MedicalUnited Statesgeographic distributionmycobacterial infectionsopportunistic plumbing pathogenssurface water

Identifiers

PMID31683836
PMCPMC6862550
OpenAlexW2983859055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.