Evidence map›Paper›PMID 31683779›Full record

Trial reportNutrients2019

Amino Acid Availability of a Dairy and Vegetable Protein Blend Compared to Single Casein, Whey, Soy, and Pea Proteins: A Double-Blind, Cross-Over Trial.

Jue Liu, Marianne Klebach, Monique Visser, Zandrie Hofman

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05669612 (Promephy - Metabolic Fate of Plant-based Proteins), which is not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05669612 nacompletednot on this mapstarted 2023, after this paper: background citation

Promephy - Metabolic Fate of Plant-based Proteins

TypeinterventionalSponsorAnglia Ruskin UniversityRan2023 to 2024Enrolled20ConditionsAmino Acid Change, Gastrointestinal DysfunctionArmsDairy based protein, Mixed protein, Plant-based protein 1, Plant-based protein 2
3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  19. Term infant formula macronutrient composition: An update for clinicians.Journal of pediatric gastroenterology and nutrition · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jue LiuDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. jue.liu@nutricia.com.ORCID 0000-0003-2146-6785
Marianne KlebachDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. marianne.klebach@danone.com.
Monique VisserDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. Monique.Visser@danone.com.
Zandrie HofmanDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. zandrie.hofman@nutricia.com.ORCID 0000-0002-4035-3471

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein quality is important for patients needing medical nutrition, especially those dependent on tube feeding. A blend of dairy and vegetable proteins (35% whey, 25% casein, 20% soy, 20% pea; P4) developed to obtain a more balanced amino acid profile with higher chemical scores, was compared to its constituent single proteins. Fourteen healthy elderly subjects received P4, whey, casein, soy, and pea (18 g/360 mL bolus) on five separate visits. Blood samples were collected at baseline until 240 min after intake. Amino acid availability was calculated using incremental maximal concentration (

Indexed as

AgedAmino AcidsAnimalsBiological AvailabilityCaseinsCross-Over StudiesDietary ProteinsDouble-Blind MethodFemaleGlycine maxHumansMaleMilkPea ProteinsPisum sativumSoybean ProteinsAmino AcidsCaseinsDietary ProteinsPea ProteinsSoybean ProteinsWhey Proteinsamino acid compositionarginineenteral tube feedglycineleucinemethioninenon-essential amino acidprotein blendprotein qualityvegetable protein

Identifiers

PMID31683779
PMCPMC6893549

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.