Evidence map›Paper›PMID 31683761›Full record

ArticleInternational journal of molecular sciences2019

In Vitro Evaluation and Docking Studies of 5-oxo-5

Malose J Mphahlele, Samantha Gildenhuys, Emmanuel N Agbo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Therapeutic Candidates for Alzheimer's Disease: Saponins.International journal of molecular sciences · 2023
    Review
  2. Review
  3. Review
  4. Review
  5. Biochemical Characterization of 13-Lipoxygenases ofInternational journal of molecular sciences · 2021
    Article
  6. Synthesis of New 3-Arylcoumarins BearingFrontiers in chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Malose J MphahleleDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa. mphahmj@unisa.ac.za.ORCID 0000-0002-6018-5671
Samantha GildenhuysDepartment of Life & Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Private Bag X06, Florida 1710, South Africa. gildes@unisa.ac.za.ORCID 0000-0002-9717-8379
Emmanuel N AgboDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa. piruesbest@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel 2-carbo-substituted 5-oxo-5

Indexed as

Molecular Docking SimulationAcetylcholinesteraseAlzheimer DiseaseAmyloid Precursor Protein SecretasesArachidonate 5-LipoxygenaseButyrylcholinesteraseCell SurvivalCholinesterase InhibitorsHumansKineticsLipoxygenase InhibitorsMCF-7 CellsMolecular StructureStructure-Activity RelationshipAcetylcholinesteraseALOX5 protein, humanAmyloid Precursor Protein SecretasesArachidonate 5-LipoxygenaseButyrylcholinesteraseCholinesterase InhibitorsLipoxygenase Inhibitors5H-furo[3,2-g]chromen-5-onesanti-oxidantcholinesterasescytotoxicitylipoxygenasesmolecular dockingβ-secretase

Identifiers

PMID31683761
PMCPMC6862662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.