Evidence map›Paper›PMID 31683730›Full record

ReviewDiagnostics (Basel, Switzerland)2019

Surveillance of Individuals with a Family History of Pancreatic Cancer and Inherited Cancer Syndromes: A Strategy for Detecting Early Pancreatic Cancers.

Hiroyuki Matsubayashi, Yoshimi Kiyozumi, Hirotoshi Ishiwatari, Katsuhiko Uesaka, Masataka Kikuyama, Hiroyuki Ono

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Bromelain and acetylcysteine (BromAcAmerican journal of translational research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroyuki MatsubayashiDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka 411-8777, Japan. h.matsubayashi@scchr.jp.
Yoshimi KiyozumiDivision of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka 411-8777, Japan. y.kiyozumi@scchr.jp.
Hirotoshi IshiwatariDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka 411-8777, Japan. h.ishiwatari@scchr.jp.
Katsuhiko UesakaDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka 411-8777, Japan. k.uesaka@scchr.jp.
Masataka KikuyamaDepartment of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo 113-0021, Japan. kikuyama110@yahoo.ne.jp.
Hiroyuki OnoDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka 411-8777, Japan. h.ono@scchr.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A family history of pancreatic cancer (PC) is a risk factor of PC, and risk levels increase as affected families grow in number and/or develop PC at younger ages. Familial pancreatic cancer (FPC) is defined as a client having at least two PC cases in a first degree relatives. In the narrow sense, FPC does not include some inherited cancer syndromes that are known to increase the risks of PC, such as Peutz-Jeghers syndrome (PJS), hereditary pancreatitis (HP), hereditary breast ovarian cancer syndrome (HBOC), and so on. FPC accounts for 5%-10% of total PC diagnoses and is marked by several features in genetic, epidemiological, and clinicopathological findings that are similar to or distinct from conventional PC. Recent advances in genetic medicine have led to an increased ability to identify germline variants of cancer-associated genes. To date, high-risk individuals (HRIs) in many developed countries, including FPC kindreds and inherited cancer syndromes, are screened clinically to detect and treat early-stage PC. This article highlights the concept of FPC and the most recent data on its detection.

Indexed as

familial pancreatic cancergenetichigh risksurveillancetreatment

Identifiers

PMID31683730
PMCPMC6963266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.