Evidence map›Paper›PMID 31683701›Full record

ReviewInternational journal of molecular sciences2019

Conjunctival Melanoma: Genetic and Epigenetic Insights of a Distinct Type of Melanoma.

Ernesto Rossi, Giovanni Schinzari, Brigida Anna Maiorano, Monica Maria Pagliara, Alessandro Di Stefani, Emilio Bria, Ketty Peris, Maria Antonietta Blasi, Giampaolo Tortora

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 53 citations in OpenAlex.

  1. Ocular Melanoma: A Comprehensive Review with a Focus on Molecular Biology.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Review
  4. Subepithelial Lesions of the Ocular Surface: A Review.Current ophthalmology reports · 2025
    Review
  5. Review
  6. Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. 5-Hydroxymethylcytosine Loss in Conjunctival Melanoma.Dermatopathology (Basel, Switzerland) · 2021
    Article
  16. Molecular Genetics of Conjunctival Melanoma and Prognostic Value ofInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ernesto RossiMedical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. ernesto.rossi@policlinicogemelli.it.
Giovanni SchinzariMedical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. giovanni.schinzari@unicatt.it.
Brigida Anna MaioranoMedical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. brigim@hotmail.it.
Monica Maria PagliaraOphtalmology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. monicamaria.pagliara@policlinicogemell.
Alessandro Di StefaniDermatology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. alessandro.distefani@gmail.com.
Emilio BriaMedical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. emilio.bria@unicatt.it.
Ketty PerisDermatology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. ketty.peris@unicatt.it.
Maria Antonietta BlasiOphtalmology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. mariaantonietta.blasi@unicatt.it.
Giampaolo TortoraMedical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. giampaolo.tortora@policlinicogemelli.it.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjunctival melanoma (CjM) is a rare, primary cancer of the ocular region. Genetic and epigenetic characteristics of conjunctival melanoma have not been completely elucidated yet. Conjunctival melanoma presents similarities with cutaneous melanoma, with substantial differences in the biological behavior. We reviewed the genetic and epigenetic insights of CjM involved in invasion and metastatic spread. CjM is commonly characterized by mutations of v-raf murine sarcoma viral oncogene homolog B1 (

Indexed as

MutationConjunctival NeoplasmsEpigenesis, GeneticGenetic Predisposition to DiseaseHumansMelanomaNeurofibromin 1Proto-Oncogene Proteins B-rafPTEN PhosphohydrolaseTelomeraseBRAF protein, humanNeurofibromin 1Proto-Oncogene Proteins B-rafPTEN PhosphohydrolasePTEN protein, humanTelomeraseBRAFconjunctivalEZH2geneticmelanomamiRNANF1NRAS

Identifiers

PMID31683701
PMCPMC6862213
OpenAlexW2982675491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.