Evidence map›Paper›PMID 31683582›Full record

ReviewNanomaterials (Basel, Switzerland)2019

Nanotechnology in Oral Cavity Carcinoma: Recent Trends and Treatment Opportunities.

Francesca De Felice, Costanza Cavallini, Alberta Barlattani, Mario Tombolini, Orlando Brugnoletti, Vincenzo Tombolini, Antonella Polimeni

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca De FeliceDepartment of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. fradefelice@hotmail.it.
Costanza CavalliniDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. costanza.cavallini@uniroma1.it.
Alberta BarlattaniDepartment of Clinical Sciences and Translational Medicine, Tor Vergata University, 00133 Rome, Italy. alberta.barlattani@ptvonline.it.
Mario TomboliniDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. mario.tombolini@uniroma1.it.
Orlando BrugnolettiDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. orlando.brugnoletti@uniroma1.it.
Vincenzo TomboliniDepartment of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. vincenzo.tombolini@uniroma1.it.
Antonella PolimeniDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. antonella.polimeni@uniroma1.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cavity carcinoma (OCC) remains an ongoing public health problem. Emerging nanotechnology provides alternative treatment approaches. This review covers the up-to-date literature in the human OCC treatment field. We explored the growing body of evidence to reveal novel and highly promising diagnostic and therapeutic applications of nanotechnology in this field. Various types of nanoparticles have been tested for applications in OCC. Imaging modalities in addition to nanocarriers are discussed. The encouraging contribution of lymphotropic nanoparticles contrast in the diagnosis of metastatic cervical lymph nodes needs to be confirmed. The development of the sentinel lymph node procedure and photodynamic therapy may lead to breakthrough therapies in order improve clinical outcomes and quality of life. In this perspective, cancer nanotechnology has the potential to revolutionize the treatment of OCC patients.

Indexed as

diagnostic examimagingnanoparticlenanotechnologyoral cavity cancerphotodynamic therapyradiotherapyresearchsentinel lymph nodesurgery

Identifiers

PMID31683582
PMCPMC6915589

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.