Evidence map›Paper›PMID 31683184›Full record

ArticleGait & posture2020

Chronic obstructive pulmonary disease patients increase medio-lateral stability and limit changes in antero-posterior stability to curb energy expenditure.

Farahnaz Fallahtafti, Carolin Curtze, Kaeli Samson, Jennifer M Yentes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gait & posture, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician.International journal of chronic obstructive pulmonary disease · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farahnaz FallahtaftiDepartment of Biomechanics, University of Nebraska at Omaha, 6160 University Drive South, Omaha, NE 68182-0860, United States. Electronic address: ffallahtafti@unomaha.edu.
Carolin CurtzeDepartment of Biomechanics, University of Nebraska at Omaha, 6160 University Drive South, Omaha, NE 68182-0860, United States. Electronic address: ccurtze@unomaha.edu.
Kaeli SamsonDepartment of Biostatistics, University of Nebraska Medical Center, 984375 Nebraska Medical Center, Omaha, NE 68198-4375, United States. Electronic address: kksamson@unmc.edu.
Jennifer M YentesDepartment of Biomechanics, University of Nebraska at Omaha, 6160 University Drive South, Omaha, NE 68182-0860, United States. Electronic address: jyentes@gmail.com.

Funding

Visual control of locomotion in people with Parkinsons diseaseP20GM109090 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI STERGIOU, NIKOLAOS · 2014 to 2023
$20.5M
NHLBI NIH HHS L30 HL129255NIGMS NIH HHS P20 GM109090
6 · The paper itself

Abstract

backgroundA relationship exists between step width and energy expenditure, yet the contribution of dynamic stability to energy expenditure is not completely understood. Chronic obstructive pulmonary disease (COPD) patients' energy expenditure is increased due to airway obstruction. Further, they have a higher prevalence of falls and balance deficits compared to controls. RESEARCH QUESTION: Is dynamic stability different between COPD patients and controls; and is the association between dynamic stability and energy expenditure different between groups?

methodsSeventeen COPD patients (64.3 ± 7.6years) and 23 controls (59.9 ± 6.6years) walked on a treadmill at three speeds: self-selected walking speed (SSWS), -20%SSWS, and +20%SSWS. Mean and variability (standard deviation) of the anterior-posterior (AP) and medio-lateral (ML) margins of stability (MOS) were compared between groups and speed conditions, while controlling for covariates. Additionally, their association to metabolic power was examined.

resultsThe association between stability and power did not significantly differ between groups. However, increased metabolic power was associated with decreased MOS AP mean (p < 0.0001), independent of speed. Increased MOS AP variability (p = 0.01) and increased SSWS (p's < 0.05) were associated with increased metabolic power. The MOS ML mean for COPD patients was greater than that of healthy patients (p = 0.02). MOS AP mean decreased as speed increased and differed by group (p = 0.048). For COPD patients, a plateau was observed at SSWS and did not decrease further at +20%SSWS compared to controls. MOS AP variability (p < 0.0001), MOS ML mean (p < 0.0001), and MOS ML variability (p = 0.003) decreased as speed increased and did not differ by group. SIGNIFICANCE: Patients with COPD operate at the upper limit of their metabolic reserve due to an increased cost of breathing. To compensate for their lack of stability, they walked with larger margins of stability in the ML direction, instead of changing the stability margins in the AP direction, due to its association with energy expenditure.

Indexed as

AgedCase-Control StudiesEnergy MetabolismExercise TestFemaleHumansLinear ModelsMaleMiddle AgedPostural BalancePulmonary Disease, Chronic ObstructiveWalkingWalking SpeedDynamic stabilityExtrapolated center of massMetabolic powerPulmonary disease

Identifiers

PMID31683184
PMCPMC6889081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.