Evidence map›Paper›PMID 31682405›Full record

ReviewBioconjugate chemistry2020

Recent Advances in Molecular Imaging with Gold Nanoparticles.

Mathilde Bouché, Jessica C Hsu, Yuxi C Dong, Johoon Kim, Kimberly Taing, David P Cormode

Abstract readReview
In one paragraph

Review in Bioconjugate chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Exploring the Coating of Gold Nanoparticles with Lipids.Nanomaterials (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Frontiers in chemistry · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. [Molecules (Basel, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Funding

Nanoparticle contrast agents for earlier breast cancer detectionR01CA227142 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CORMODE, DAVID PETER · 2018 to 2022
$2.5M
Biodegradable polymetal nanoparticle CT contrast agents for vascular imagingR01HL131557 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CORMODE, DAVID PETER · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA227142NHLBI NIH HHS R01 HL131557
6 · The paper itself

Abstract

Gold nanoparticles (AuNP) have been extensively developed as contrast agents, theranostic platforms, and probes for molecular imaging. This popularity has yielded a large number of AuNP designs that vary in size, shape, surface functionalization, and assembly, to match very closely the requirements for various imaging applications. Hence, AuNP based probes for molecular imaging allow the use of computed tomography (CT), fluorescence, and other forms of optical imaging, photoacoustic imaging (PAI), and magnetic resonance imaging (MRI), and other newer techniques. The unique physicochemical properties, biocompatibility, and highly developed chemistry of AuNP have facilitated breakthroughs in molecular imaging that allow the detection and imaging of physiological processes with high sensitivity and spatial resolution. In this Review, we summarize the recent advances in molecular imaging achieved using novel AuNP structures, cell tracking using AuNP, targeted AuNP for cancer imaging, and activatable AuNP probes. Finally, the perspectives and current limitations for the clinical translation of AuNP based probes are discussed.

Indexed as

AnimalsCell TrackingGoldHumansMagnetic Resonance ImagingMetal NanoparticlesMolecular ImagingOptical ImagingPhotoacoustic TechniquesTomography, X-Ray ComputedGold

Identifiers

PMID31682405
PMCPMC7032998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.