Evidence map›Paper›PMID 31681890›Full record

ArticleACS omega2019

Iodocyclization in Aqueous Media and Supramolecular Reaction Control Using Water-Soluble Hosts.

Treyvon Bokoskie, Christopher Cunningham, Cory Kornman, Tanay Kesharwani, Mahesh Pattabiraman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Treyvon BokoskieDepartment of Chemistry, University of Nebraska Kearney, Kearney, Nebraska 68849, United States.
Christopher CunninghamDepartment of Chemistry, University of West Florida, Pensacola, Florida 32514, United States.
Cory KornmanDepartment of Chemistry, University of West Florida, Pensacola, Florida 32514, United States.
Tanay KesharwaniDepartment of Chemistry, University of West Florida, Pensacola, Florida 32514, United States.
Mahesh PattabiramanDepartment of Chemistry, University of Nebraska Kearney, Kearney, Nebraska 68849, United States.
University of West Florida · USUniversity of Nebraska at Kearney · US

Funding

MARC at University of West FloridaT34GM110517 · NIGMS · UNIVERSITY OF WEST FLORIDA · PI CAVNAR, PETER J., MOLEK, KAREN SINCLAIR · 2014 to 2023
$2.6M
NIGMS NIH HHS T34 GM110517
6 · The paper itself

Abstract

Iodocyclization of 2-alkynylanisoles is an efficient route for synthesizing substituted benzofurans. Reaction efficiency with copper(II) sulfate and sodium iodide in an aqueous slurry under mild conditions is a manifold higher than in organic solvents. Water-soluble hosts of the cyclodextrin family solubilize the compounds in aqueous media and affect the reaction efficiency through conformation control and steric interactions. Computational chemistry and spectral titration provide information on the host-guest complex structure and insight into the mechanistic basis of the observed effects.

Identifiers

PMID31681890
PMCPMC6822118
OpenAlexW2980947539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.