Evidence map›Paper›PMID 31681876›Full record

ArticleACS omega2019

Montmorillonites Can Tightly Bind Glyphosate and Paraquat Reducing Toxin Exposures and Toxicity.

Meichen Wang, Asuka A Orr, Shujun He, Chimeddulam Dalaijamts, Weihsueh A Chiu, Phanourios Tamamis, Timothy D Phillips

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Meichen WangVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Asuka A OrrVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Shujun HeVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Chimeddulam DalaijamtsVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Weihsueh A ChiuVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Phanourios TamamisVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Timothy D PhillipsVeterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences and Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Texas A&M University · US

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Thomas Joseph McDonald · 2017 to 2026
$21.2M
NIEHS NIH HHS P42 ES027704
6 · The paper itself

Abstract

Among the numerous contaminants of soil, glyphosate and paraquat are two of the most widely used herbicides that are commonly detected in the environment. Soil and sediment contaminated with glyphosate, paraquat, and other environmental toxins can be mobilized and redistributed to lawns, vegetable gardens, parks, and water supplies in vulnerable communities at the site of disasters such as hurricanes and flooding. Glyphosate and paraquat bind strongly to soils containing clays, making their bioavailability (bioaccessibility) from these types of soil very low. Because of their affinity for clay-based soils, it is possible that montmorillonite clays could be administered as a therapeutic agent in the diet of animals and humans to decrease short-term exposure and toxicity. In this study, we investigated the sorption mechanisms of glyphosate and paraquat onto active surfaces of calcium montmorillonite (CM) and sodium montmorillonite (SM) clays and derived binding parameters, including capacity, affinity, and enthalpy. Additionally, we used these parameters to predict the reduction in bioavailability under different pH and temperature conditions and to estimate the theoretical dose of clay that could protect against severe paraquat toxicity and lethality. Computational modeling and simulation studies depicted toxin sorption mechanisms at different pH values. Additionally, a toxin-sensitive living organism (

Identifiers

PMID31681876
PMCPMC6822125
OpenAlexW2980345487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.