Evidence map›Paper›PMID 31681831›Full record

ArticleEndoscopy international open2019

Neoadjuvant cryotherapy improves dysphagia and may impact remission rates in advanced esophageal cancer.

Tilak Shah, Vladimir Kushnir, Pritesh Mutha, Mankanchan Majhail, Bhaumik Patel, Matthew Schutzer, Drew Mogahanaki, George Smallfield, Milan Patel, Alvin Zfass

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07222657 (Phase 2 Randomized Trial Of Liquid Nitrogen Spray Cryotherapy Prior To Neoadjuvant Systemic Therapy In Locally Advanced Esophageal Adenocarcinoma), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07222657 phase2recruitingnot on this mapstarted 2026, after this paper: background citation

Phase 2 Randomized Trial Of Liquid Nitrogen Spray Cryotherapy Prior To Neoadjuvant Systemic Therapy In Locally Advanced Esophageal Adenocarcinoma

TypeinterventionalSponsorCase Comprehensive Cancer CenterRan2026 to 2027Enrolled40ConditionsEsophageal Adenocarcinoma, Esophageal CancerArmsStandard of care chemotherapy, LNSC
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Freezing our way to a cure?iGIE : innovation, investigation and insights · 2024
    Review
  8. Article
  9. Stenting for Esophageal Cancer.Gastroenterology & hepatology · 2023
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Tilak ShahDivision of Gastroenterology, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
Vladimir KushnirSection of Gastroenterology, Washington University in St. Louis, St. Louis, Missouri, United States.
Pritesh MuthaDivision of Gastroenterology, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
Mankanchan MajhailDivision of Gastroenterology, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
Bhaumik PatelMassey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States.
Matthew SchutzerRadiation oncology Service, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
Drew MogahanakiRadiation oncology Service, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
George SmallfieldDivision of Gastroenterology, Virginia Commonwealth University Health System.
Milan PatelDepartment of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, United States.
Alvin ZfassDivision of Gastroenterology, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia, United States.
Hunter Holmes McGuire VA Medical Center · USVirginia Commonwealth University · USUniversity Health System · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID31681831
PMCPMC6823095
OpenAlexW2987967864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.