Evidence map›Paper›PMID 31681671›Full record

ArticleJournal of family medicine and primary care2019

Association of 4-basepair G-to-A transition in the 5'-untranslated region of ANKH gene with selected patients of primary knee osteoarthritis: A cross sectional study.

Puneet Kumar, Aarti Sharma, Siddharth Das, Ragini Srivastava, Nikhil Gupta

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Puneet KumarDepartment of Rheumatology, King George Medical University, Lucknow, Uttar Pradesh, India.
Aarti SharmaDepartment of Rheumatology, All India Institute of Medical Sciences, New Delhi, India.
Siddharth DasDepartment of Rheumatology, King George Medical University, Lucknow, Uttar Pradesh, India.
Ragini SrivastavaDepartment of Rheumatology, King George Medical University, Lucknow, Uttar Pradesh, India.
Nikhil GuptaDepartment of Rheumatology, Post Doctoral Fellow Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodA cohort study was carried out for a year to evaluate the presence of G-to-A transition in 5'-untranslated region of ankylosis human (

resultsIn the total participants, 25 were Khatri primary knee OA patients (cases) residing in Lucknow and 101 were random blood donors' samples (controls) collected from a blood bank. All were studied for the abovementioned mutation using real-time polymerase chain reaction (RT-PCR). GG genotype was present in 72.3% of controls and 76% of Khatri knee OA patients. The studied G-to-A mutation was found to be positive in 24.8% of controls and 16% of cases, odds ratio (95% confidence interval) being 0.6 (0.19-1.98,

conclusionThis study did not show any significant G to A mutation in the studied subjects.

Indexed as

Ankylosis humanchondrocalcinosisgenotypeKhatriOAosteoarthritis

Identifiers

PMID31681671
PMCPMC6820404

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