Evidence map›Paper›PMID 31681631›Full record

ArticleFrontiers in cellular and infection microbiology2019

Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in

Ye-Eun Son, Ci Fu, Won-Hee Jung, Sang-Hun Oh, Jin-Hwan Kwak, Maria E Cardenas, Joseph Heitman, Hee-Soo Park

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ye-Eun SonSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu, South Korea.
Ci FuDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States.
Won-Hee JungSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu, South Korea.
Sang-Hun OhSchool of Life Science, Handong Global University, Pohang, South Korea.
Jin-Hwan KwakSchool of Life Science, Handong Global University, Pohang, South Korea.
Maria E CardenasDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States.
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States.
Hee-Soo ParkSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu, South Korea.
Kyungpook National University · KRDuke Medical Center · USHandong Global University · KRDuke University Hospital · US

Funding

Novel Antifungal Therapeutic ApproachesR01AI050438 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2001 to 2012
$3.3M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR01AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, SCHUMACHER, MARIA · 2014 to 2017
$2.5M
Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transportersR01CA154499 · NCI · DUKE UNIVERSITY · PI CARDENAS-CORONA, MARIA E · 2011 to 2015
$1.6M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR56AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, HONG, JIYONG · 2020 to 2020
$669k
NCI NIH HHS R01 CA154499NIAID NIH HHS R01 AI050438NIAID NIH HHS R01 AI112595NIAID NIH HHS R56 AI112595
6 · The paper itself

Abstract

The Mkt1-Pbp1 complex promotes mating-type switching by regulating the translation of

Indexed as

Genes, Mating Type, FungalCarrier ProteinsCryptococcosisCryptococcus neoformansFungal ProteinsGene Expression Regulation, FungalMutationProtein BindingVirulenceCarrier ProteinsFungal ProteinsCryptococcus neoformansMkt1Pbp1sexual reproductionvirulence

Identifiers

PMID31681631
PMCPMC6811503
OpenAlexW2981162821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.