Evidence map›Paper›PMID 31681571›Full record

ArticleFrontiers in oncology2019

Multi-omics Analysis of Microenvironment Characteristics and Immune Escape Mechanisms of Hepatocellular Carcinoma.

Wenli Li, Huimei Wang, Zhanzhong Ma, Jian Zhang, Wen Ou-Yang, Yan Qi, Jun Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 90 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wenli LiDepartment of Reproductive Medicine Center, Yue Bei People's Hospital, Shaoguan, China.
Huimei WangMorning Star Academic Cooperation, Shanghai, China.
Zhanzhong MaDepartment of Clinical Laboratory, Yue Bei People's Hospital, Shaoguan, China.
Jian ZhangDepartment of Clinical Laboratory, Yue Bei People's Hospital, Shaoguan, China.
Wen Ou-YangMorning Star Academic Cooperation, Shanghai, China.
Yan QiYunnan Provincial Key Laboratory of Traditional Chinese Medicine Clinical Research, First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Jun LiuDepartment of Clinical Laboratory, Yue Bei People's Hospital, Shaoguan, China.
Shantou University · CNShanghai Medical College of Fudan University · CNSouthern Medical University · CNYunnan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune environment in primary tumor has a profound impact on immunotherapy. However, the clinical relevance of immune environment in hepatocellular carcinoma (HCC) is largely unknown. Here, the immune profile and its clinical response in HCC were investigated. The gene expression profiles of 569 HCCs from three cohorts (The Cancer Genome Atlas, TCGA,

Indexed as

bioinformatics analysiscancer stagehepatocellular carcinomaimmune-enhanced subtypeimmune escapemolecular subtype

Identifiers

PMID31681571
PMCPMC6803502
OpenAlexW2979840381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.