Evidence map›Paper›PMID 31681544›Full record

ArticleInternational journal of applied & basic medical research

A Study on Hepatitis B Viral Seromarkers and Associated Risk Factors among the Patients Suffering from Acute and Chronic Hepatitis B Infection.

P Prabina, S Jayanthi, C Krishna Murthy, S Babu Kumar, As Shameem Banu, S R Sakunthala, J Perumal

Abstract read
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Article in International journal of applied & basic medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

P PrabinaDepartment of Microbiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.
S JayanthiDepartment of Microbiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.
C Krishna MurthyDepartment of Microbiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.
S Babu KumarDepartment of Gastroenterology, Chettinad Super Speciality Hospital, Kelambakkam, Tamil Nadu, India.
As Shameem BanuDepartment of Microbiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.
S R SakunthalaDepartment of General Medicine, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.
J PerumalDepartment of Microbiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis B viral infection is the most common cause of hepatitis, and it leads to serious liver diseases such as cirrhosis and hepatocellular carcinoma.

aimThe aim of the study is to differentiate acute hepatitis B and chronic hepatitis B (CHB) among patients seropositive for hepatitis B surface antigen (HBsAg). MATERIALS AND

methodsThis study was carried out in the Department of Microbiology, Chettinad Hospital and Research Institute, Kelambakkam, Tamil Nadu, India, for a period of 6 months (January 2018-June 2018). Blood samples were collected from 87 patients for the detection of hepatitis B virus (HBV) serological markers. HBsAg, hepatitis B e antigen (HBeAg), anti-HBc total, anti-HBc IgM, and antibody to hepatitis B surface antigen were screened using the ELISA method. Detailed demographic profile including history of previous hepatitis infection, previous blood transfusion, and other related details were collected and documented using a structured questionnaire.

resultsA total of 87 patients were HBsAg seropositive; among them, 55 (63.2%) were male and 32 (36.9%) were female. Based on the serological markers tested, 24 and 63 were suffering from acute and chronic HBV infections, respectively. Among the acute hepatitis B patients, all samples were seropositive for HBsAg, anti-HBc total, and anti-HBc IgM. HBeAg seromarker was found in 15 patients (62.5%). Among the CHB patients, all samples were seropositive for HBsAg and anti-HBc total. HBeAg seromarker was found in 28 patients with 44.4%. Alcohol consumption was the major risk factor for the transmission of HBV infection.

conclusionAn increased sample size and detailed study of high-risk behavior will provide an alarming awareness of their association.

Indexed as

Acute hepatitis B virus infectionchronic hepatitis B infectionhepatitis B virusserological markers

Identifiers

PMID31681544
PMCPMC6822324

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