Evidence map›Paper›PMID 31681417›Full record

ArticleFrontiers in genetics2019

The Long Noncoding RNA

Stephanie M Bilinovich, Kristy Lewis, Nicole Grepo, Daniel B Campbell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Sex- and age-dependent contribution of System xFrontiers in behavioral neuroscience · 2023
    Article
  6. Article
  7. Emerging Role of Non-coding RNAs in Autism Spectrum Disorder.Journal of molecular neuroscience : MN · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stephanie M BilinovichDepartment of Pediatrics and Human Development, Michigan State University, Grand Rapids, MI, United States.
Kristy LewisDepartment of Pediatrics and Human Development, Michigan State University, Grand Rapids, MI, United States.
Nicole GrepoCenter for Gene Therapy, City of Hope, Duarte, CA, United States.
Daniel B CampbellDepartment of Pediatrics and Human Development, Michigan State University, Grand Rapids, MI, United States.
Michigan State University · USCity of Hope · US

Funding

Non-Coding RNAs in AutismR21MH099504 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CAMPBELL, DANIEL BRIAN · 2013 to 2014
$451k
Biology of Non-Coding RNAs Associated with Psychiatric DisordersR56ES029064 · NIEHS · MICHIGAN STATE UNIVERSITY · PI CAMPBELL, DANIEL BRIAN · 2018 to 2018
$217k
NIEHS NIH HHS R56 ES029064NIMH NIH HHS R21 MH099504
6 · The paper itself

Abstract

Most of the genetic risk for autism spectrum disorder (ASD) is inherited as common genetic variants, although some rare mutations have been identified in individuals with ASD. Common genetic variants are most parsimoniously identified by genome wide association studies. Genome wide association studies have identified several genetic loci with genome wide association with ASD. However, genome wide association studies only identify regions of the genome associated with phenotypic traits. Identification of the functional elements requires additional experimental evidence. Here, we demonstrate that a genome wide association study locus for ASD on chromosome 20p12.1, rs4141463, implicates a noncoding RNA as a functional element. Although rs4141463 lies within an intron of the protein-coding

Indexed as

autismbraindevelopmentenvironmentepigeneticsgeneticslncRNAnoncoding RNA

Identifiers

PMID31681417
PMCPMC6804435
OpenAlexW2981236306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.