ArticleFrontiers in genetics2019
Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders.
Open access · goldAbstract read
In one paragraph
Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 50 citations in OpenAlex.
- Genome-Wide DNA Methylation Profiling of Peripheral Blood Mononuclear Cells Reveals Epigenetic Signatures in Autism Spectrum Disorder.International journal of molecular sciences · 2026Article
- Article
- Review
- Structural pathways related to the subventricular zone are decreased in volume with altered microstructure in young adult males with autism spectrum disorder.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- DNA Methylation in Autism Spectrum Disorders: Biomarker or Pharmacological Target?Brain sciences · 2024Review
- Traversing the epigenetic landscape: DNA methylation from retina to brain in development and disease.Frontiers in cellular neuroscience · 2024Review
- Exploring the epigenetic landscape: The role of 5-hydroxymethylcytosine in neurodevelopmental disorders.Cambridge prisms. Precision medicine · 2024Review
- Intercontinental insights into autism spectrum disorder: a synthesis of environmental influences and DNA methylation.Environmental epigenetics · 2024Review
- Exploratory analysis of L1 retrotransposons expression in autism.Molecular autism · 2023Article
- 7p22.2 Microduplication: A Pathogenic CNV?Genes · 2023Article
- Article
- In individuals with Williams syndrome, dysregulation of methylation in non-coding regions of neuronal and oligodendrocyte DNA is associated with pathology and cortical development.Molecular psychiatry · 2023Article
- Epigenetics of Autism Spectrum Disorders: A Multi-level Analysis Combining Epi-signature, Age Acceleration, Epigenetic Drift and Rare Epivariations Using Public Datasets.Current neuropharmacology · 2023Article
- Future Prospects for Epigenetics in Autism Spectrum Disorder.Molecular diagnosis & therapy · 2022Review
- LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes.Scientific reports · 2022Article
- Small Nucleus Accumbens and Large Cerebral Ventricles in Infants and Toddlers Prior to Receiving Diagnoses of Autism Spectrum Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism.Genome biology · 2022Article
- Integration of structural MRI and epigenetic analyses hint at linked cellular defects of the subventricular zone and insular cortex in autism: Findings from a case study.Frontiers in neuroscience · 2022Article
- Diethylstilbestrol and autism.Frontiers in endocrinology · 2022Review
- Re-emerging concepts of immune dysregulation in autism spectrum disorders.Frontiers in psychiatry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Michael J CorleyDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Nauru Vargas-MayaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Alina P S PangDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Annette Lum-JonesDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Dongmei LiDepartment of Clinical and Translational Research, University of Rochester Medical Center, Rochester, NY, United States.
Vedbar KhadkaOffice of Biostatistics & Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
Razvan SultanaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
D Caroline BlanchardBekesy Neurobiology Laboratory, Pacific Biosciences Research Center, University of Hawaii at Manoa, Honolulu, HI, United States.
Alika K MaunakeaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States.
University of Hawaiʻi at Mānoa · USUniversity of Rochester Medical Center · US
Funding
UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3MThe Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Noemi Polgar · 2017 to 2026
$59.5MTRPA1 Physiology in Diabetes, Metabolic Syndrome, and MetabolismP20GM113134 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Jaques Schunke · 2017 to 2026
$21.5MTransgenic Mouse, ICSI and IVF CoreP20GM103457 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI MOISYADI, STEFAN · 2012 to 2018
$12.9MTranslational Pilot Project ProgramP30GM131944 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI WARD, WILLIAM S · 2019 to 2023
$5.9MThe role of epigenetic transcriptional memory in monocyte-macrophage cells and cardiovascular disease riskK01HL140271 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CORLEY, MICHAEL JAY · 2018 to 2022
$788kEpigenomic Dysregulation of Neurodevelopmental Genes Underlies Autism Spectrum DisordersR21MH114005 · NIMH · UNIVERSITY OF HAWAII AT MANOA · PI MAUNAKEA, ALIKA KEOLAOKALANI · 2017 to 2018
$424kNHLBI NIH HHS K01 HL140271NIGMS NIH HHS P20 GM103457NIGMS NIH HHS P20 GM103466NIGMS NIH HHS P20 GM113134NIGMS NIH HHS P30 GM131944NIMHD NIH HHS U54 MD007601NIMH NIH HHS R21 MH114005
Abstract
Autism spectrum disorders (ASD) are hypothesized to originate
Indexed as
ASDautismDNA methylationepigeneticsneurodevelopment
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.