Evidence map›Paper›PMID 31681334›Full record

ArticleFrontiers in immunology2019

Influence of Gut Microbiota on Progression to Tuberculosis Generated by High Fat Diet-Induced Obesity in C3HeB/FeJ Mice.

Lilibeth Arias, Galo Adrián Goig, Paula Cardona, Manuela Torres-Puente, Jorge Díaz, Yaiza Rosales, Eric Garcia, Gustavo Tapia, Iñaki Comas, Cristina Vilaplana and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Article
  7. Virulence · 2024
    Review
  8. Article
  9. Article
  10. The Interplay betweenClinics and practice · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Mouse Models forPathogens (Basel, Switzerland) · 2022
    Review
  16. The Role of Gut and Lung Microbiota in Susceptibility to Tuberculosis.International journal of environmental research and public health · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Lilibeth AriasExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Galo Adrián GoigTuberculosis Genomics Unit (TGU), Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain.
Paula CardonaExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Manuela Torres-PuenteTuberculosis Genomics Unit (TGU), Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain.
Jorge DíazExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Yaiza RosalesExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Eric GarciaExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Gustavo TapiaPathology Department, Hospital Universitari Germans Trias i Pujol (HUGTIP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain.
Iñaki ComasTuberculosis Genomics Unit (TGU), Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain.
Cristina VilaplanaExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Pere-Joan CardonaExperimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Badalona, Spain.
Universitat Autònoma de Barcelona · ESInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol · ESInstituto de Biomedicina de Valencia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The administration of a high fat content diet is an accelerating factor for metabolic syndrome, impaired glucose tolerance, and early type 2 diabetes. The present study aims to assess the impact of a high fat diet on tuberculosis progression and microbiota composition in an experimental animal model using a C3HeB/FeJ mouse strain submitted to single or multiple consecutive aerosol infections. These models allowed us to study the protection induced by Bacillus Calmette-Guérin vaccination as well as by the natural immunity induced by chemotherapy after a low dose

Indexed as

AnimalsBacteriaBCG VaccineCytokinesDiabetes Mellitus, Type 2Diet, High-FatDisease Models, AnimalDisease ProgressionDysbiosisGastrointestinal MicrobiomeKaplan-Meier EstimateMice, Inbred StrainsMycobacterium tuberculosisObesityRNA, Ribosomal, 16SSequence Analysis, DNABCG VaccineCytokinesRNA, Ribosomal, 16SBCGC3HeB/FeJcomorbiditygut microbiotahigh fat dietmiceobesitytuberculosis

Identifiers

PMID31681334
PMCPMC6813253
OpenAlexW2981073089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.