Evidence map›Paper›PMID 31681311›Full record

ArticleFrontiers in immunology2019

Microbial Danger Signals Control Transcriptional Induction of Distinct MHC Class I L Lineage Genes in Atlantic Salmon.

Steingrim Svenning, Agata T Gondek-Wyrozemska, Yorick Andreas van der Wal, Børre Robertsen, Ingvill Jensen, Jorunn B Jørgensen, Eva-Stina Edholm

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Antigen Presentation and Autophagy in Teleost Adaptive Immunity.International journal of molecular sciences · 2022
    Review
  3. Why DoesFrontiers in immunology · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Steingrim SvenningNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Agata T Gondek-WyrozemskaNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Yorick Andreas van der WalNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Børre RobertsenNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Ingvill JensenNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Jorunn B JørgensenNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Eva-Stina EdholmNorwegian College of Fishery Science, Faculty of Biosciences, Fisheries & Economics, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antigen processing and presentation by major histocompatibility complex (MHC) molecules is a cornerstone in vertebrate immunity. Like mammals, teleosts possess both classical MHC class I and multiple families of divergent MHC class I genes. However, while certain mammalian MHC class I-like molecules have proven to be integral in immune regulation against a broad array of pathogens, the biological relevance of the different MHC class I lineages in fish remains elusive. This work focuses on MHC class I L lineage genes and reveals unique regulatory patterns of six genes (

Indexed as

Gene Expression RegulationGenes, MHC Class IAnimalsFish DiseasesGene Expression ProfilingHost-Pathogen InteractionsInterferon Type ILeukocytesOrgan SpecificitySalmo salarTranscriptomeInterferon Type IAtlantic salmonL-lineageMHC class IPiscirickettsia salmonisSAV3

Identifiers

PMID31681311
PMCPMC6797598
OpenAlexW2978047745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.