Evidence map›Paper›PMID 31681295›Full record

ArticleFrontiers in immunology2019

Expression of Human Mutant Huntingtin Protein in

Yu-Hsien Lin, Houda Ouns Maaroufi, Emad Ibrahim, Lucie Kucerova, Michal Zurovec

Abstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Mutation inFrontiers in cell and developmental biology · 2022
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Hsien LinBiology Centre of the Czech Academy of Sciences, Institute of Entomology, Ceske Budejovice, Czechia.
Houda Ouns MaaroufiBiology Centre of the Czech Academy of Sciences, Institute of Entomology, Ceske Budejovice, Czechia.
Emad IbrahimBiology Centre of the Czech Academy of Sciences, Institute of Entomology, Ceske Budejovice, Czechia.
Lucie KucerovaBiology Centre of the Czech Academy of Sciences, Institute of Entomology, Ceske Budejovice, Czechia.
Michal ZurovecBiology Centre of the Czech Academy of Sciences, Institute of Entomology, Ceske Budejovice, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenic effect of mutant HTT (mHTT) which causes Huntington disease (HD) are not restricted to nervous system. Such phenotypes include aberrant immune responses observed in the HD models. However, it is still unclear how this immune dysregulation influences the innate immune response against pathogenic infection. In the present study, we used transgenic

Indexed as

Gene ExpressionImmunity, HumoralAnimalsAnimals, Genetically ModifiedCell LineDrosophila melanogasterHemocytesHumansHuntingtin ProteinHTT protein, humanHuntingtin Proteinantimicrobial peptide (AMPs)cytokinesDrosophila melanogasterHuntington's diseaseimmunityinfectionphagocytosis

Identifiers

PMID31681295
PMCPMC6805700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.