Evidence map›Paper›PMID 31681240›Full record

ArticleFrontiers in microbiology2019

Lactoferrin Disaggregates Pneumococcal Biofilms and Inhibits Acquisition of Resistance Through Its DNase Activity.

Uriel A Angulo-Zamudio, Jorge E Vidal, Kamran Nazmi, Jan G M Bolscher, Claudia Leon-Sicairos, Brenda S Antezana, Adrián Canizalez-Roman, Nidia León-Sicairos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  5. Article
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  9. Innate immune responses in pneumonia.Pneumonia (Nathan Qld.) · 2023
    Review
  10. Role ofFrontiers in cellular and infection microbiology · 2023
    Review
  11. Review
  12. Lactoferrin as a Human Genome "Guardian"-An Overall Point of View.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Uriel A Angulo-ZamudioCIASaP, Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Mexico.
Jorge E VidalHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Kamran NazmiDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam, Amsterdam, Netherlands.
Jan G M BolscherDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam, Amsterdam, Netherlands.
Claudia Leon-SicairosPrograma Regional del Noroeste para el Doctorado en Biotecnología, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Culiacán, Mexico.
Brenda S AntezanaMicrobiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA, United States.
Adrián Canizalez-RomanCIASaP, Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Mexico.
Nidia León-SicairosCIASaP, Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Mexico.
Autonomous University of Sinaloa · MXPediatric Hospital of Sinaloa · MXAcademic Center for Dentistry Amsterdam · NLEmory University · USUniversity of Amsterdam · NLUniversity of Mississippi Medical Center · US

Funding

Population Dynamics of S. pneumoniae vaccine serotypes on human pharyngeal cellsR21AI112768 · NIAID · EMORY UNIVERSITY · PI VIDAL, JORGE EUGENIO · 2015 to 2016
$429k
DISSEMINATION OF MACROLIDE RESISTANCE ELEMENTS IN STREPTOCOCCUS PNEUMONIAER21AI144571 · NIAID · UNIVERSITY OF MISSISSIPPI MED CTR · PI STEPHENS, DAVID S, TZENG, YIH-LING · 2019 to 2020
$397k
NIAID NIH HHS R21 AI112768NIAID NIH HHS R21 AI144571
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

disaggregatesDNAse activitylactoferrinpneumococcal biofilmsresistance acquisition

Identifiers

PMID31681240
PMCPMC6813537
OpenAlexW2981298054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.