ArticleFrontiers in systems neuroscience2019
Intraoperative Low Alpha Power in the Electroencephalogram Is Associated With Postoperative Subsyndromal Delirium.
Article in Frontiers in systems neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05992506 (Electroencephalographic Biomarker to Predict the Development of Postoperative Delirium), which is not on this map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electroencephalographic Biomarker to Predict the Development of Postoperative Delirium: a Protocol of an Observational Study in a Cohort of Patients From Five Centers
Who cites it
36 citing papers in PubMed.
- Anesthesia-induced electroencephalogram oscillations and perioperative outcomes in older adults undergoing cardiac surgery.Journal of clinical anesthesia · 2025Trial
- Electroencephalographic guided propofol-remifentanil TCI anesthesia with and without dexmedetomidine in a geriatric population: electroencephalographic signatures and clinical evaluation.Journal of clinical monitoring and computing · 2024Trial
- Beyond processed depth targets: frontal EEG patterns, brain vulnerability, and postoperative delirium in older adults.Journal of clinical monitoring and computing · 2026Review
- Electroencephalographic Monitoring in the Recovery Room for Identification of Patients at Risk for Postoperative Delirium.Anesthesiology · 2026Observational
- Construction of a predictive model for postoperative subsyndromal delirium in patients undergoing brain tumor surgery.Acta neurologica Belgica · 2026Article
- Point-of-care electroencephalography for prediction of postoperative delirium in older adults undergoing elective surgery: protocol for a prospective cohort study.Biology methods & protocols · 2026Review
- Perioperative dynamic EEG patterns correlated with changes in cognitive subdomains.Clinical neurophysiology practice · 2026Article
- Development of a deep learning-based prediction model for postoperative delirium using intraoperative electroencephalogram in adults.NPJ digital medicine · 2025Article
- Preoperative cognitive impairment predicts deep anaesthesia and higher postoperative pain in elderly patients: an observational study.BMC anesthesiology · 2025Observational
- Prediction of postoperative delirium in older adults from preoperative cognition and occipital alpha power from resting-state electroencephalogram.Age and ageing · 2025Observational
- Age-specific electroencephalography dynamics during anesthesia: monitoring and neurocognitive implications.Anesthesia and pain medicine · 2025Review
- Article
- EEG features associated with Alzheimer's disease and Frontotemporal dementia are not reflected by processed indices used in anesthesia monitoring.Journal of clinical monitoring and computing · 2025Article
- Aperiodic component of the electroencephalogram power spectrum reflects the hypnotic level of anaesthesia. Comment on Br J Anaesth 2025; 134: 392-401.British journal of anaesthesia · 2025Article
- Associations between anaesthetic dose-adjusted intraoperative EEG alpha power, processing speed, and postoperative delirium: analysis of data from three prospective studies.British journal of anaesthesia · 2025Article
- Age-Related Electroencephalographic Delta and Alpha Oscillations During Sedation with Target-Controlled Propofol Infusion.Journal of clinical medicine · 2025Article
- Developing predictive nomogram models using quantitative electroencephalography for brain function in type a aortic dissection: a prospective observational study.International journal of surgery (London, England) · 2025Observational
- Aperiodic component of the electroencephalogram power spectrum reflects the hypnotic level of anaesthesia.British journal of anaesthesia · 2025Article
- Retrospective case-control study of intraoperative EEG correlates in postoperative delirium.Frontiers in medicine · 2025Article
- Incidence and influencing factors of subsyndromal delirium in elderly patients with pancreatic surgery: a prospective study.Frontiers in psychiatry · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative delirium (PD) and subsyndromal delirium (PSSD) are frequent complications in older patients associated with poor long-term outcome. It has been suggested that certain electroencephalogram features may be capable of identifying patients at risk during surgery. Thus, the goal of this study was to characterize intraoperative electroencephalographic markers to identify patients prone to develop PD or PSSD.
methodsWe conducted an exploratory observational study in older patients scheduled for elective major abdominal surgery. Intraoperative 16 channels electroencephalogram was recorded, and PD/PSSD were diagnosed after surgery with the confusion assessment method (CAM). The total power spectra and relative power of alpha band were calculated.
resultsPD was diagnosed in 2 patients (6.7%), and 11 patients (36.7%) developed PSSD. All of them (13 patients, PD/PSSD group) were compared with patients without any alterations in CAM (17 patients, control group). There were no detectable power spectrum differences before anesthesia between both groups of patients. However, PD/PSSD group in comparison with control group had a lower intraoperative absolute alpha power during anesthesia (4.4 ± 3.8 dB vs. 9.6 ± 3.2 dB, DISCUSSION: In conclusion, a low intraoperative alpha power is a novel electroencephalogram marker to identify patients who will develop alterations in CAM - i.e., with PD or PSSD - after surgery.
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