ReviewFrontiers in neural circuits2019
The Growing Evidence for the Importance of the Otoliths in Spatial Memory.
Review in Frontiers in neural circuits, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Exploring a world turned upside down: a shift to egocentric navigation.Scientific reports · 2026Article
- Associations Between Vestibular Function and White Matter Microstructure in Healthy Older Adults.medRxiv : the preprint server for health sciences · 2025Article
- Reduced Vestibular Function is Associated With Cortical Surface Shape Changes in the Frontal Cortex.Human brain mapping · 2025Article
- The Inner Ear and Aging Brain: A Cross-Sectional Study of Vestibular Function and Morphometric Variations in the Entorhinal and Trans-Entorhinal Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Comparison of virtual reality and real environment effects on perception of height in healthy individuals.PloS one · 2025Article
- Development of Spatial Memory: A Behavioral Study.NeuroSci · 2024Article
- Reduced Vestibular Function is Associated with Cortical Surface Shape Changes in the Frontal Cortex.medRxiv : the preprint server for health sciences · 2024Article
- Constant Dizziness Versus Episodic Vertigo in Ménière's Disease: Health-Related Quality of Life, Cognitive Dissonance, and Postural Problems.The journal of international advanced otology · 2024Article
- Assessment of Otolith Function with Subjective Visual Vertical Test in Sensorineural Hearing Loss: An Analytical Cross - Sectional Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Focused Update on Clinical Testing of Otolith Organs.Audiology research · 2024Review
- Neonatal GABAergic transmission primes vestibular gating of output for adult spatial navigation.Cellular and molecular life sciences : CMLS · 2024Article
- Cognition in vestibular disorders: state of the field, challenges, and priorities for the future.Frontiers in neurology · 2024Review
- Vestibular Function is Associated with Prefrontal and Sensorimotor Cortical Gray Matter Volumes in a Cross-Sectional Study of Healthy, Older Adults.Aperture neuro · 2024Article
- Evaluating the Diagnostic Value of Electrovestibulography (EVestG) in Alzheimer's Patients with Mixed Pathology: A Pilot Study.Medicina (Kaunas, Lithuania) · 2023Article
- The impact of vestibular function on cognitive-motor interference: a case-control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing.Scientific reports · 2023Article
- Spatial orientation, postural control and the vestibular system in healthy elderly and Alzheimer's dementia.PeerJ · 2023Review
- Why Should Constant Stimulation of Saccular Afferents Modify the Posture and Gait of Patients with Bilateral Vestibular Dysfunction? The Saccular Substitution Hypothesis.Journal of clinical medicine · 2022Review
- Recent developments in the understanding of the interactions between the vestibular system, memory, the hippocampus, and the striatum.Frontiers in neurology · 2022Review
- Linking Vestibular Function and Subcortical Gray Matter Volume Changes in a Longitudinal Study of Aging Adults.Aperture neuro · 2021Article
- Self-Reported Sense of Direction and Vestibular Function in the Baltimore Longitudinal Study of Aging (BLSA).Journal of the Association for Research in Otolaryngology : JARO · 2021Article
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1 author.
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Abstract
Many studies have demonstrated that vestibular sensory input is important for spatial learning and memory. However, it has been unclear what contributions the different parts of the vestibular system - the semi-circular canals and otoliths - make to these processes. The advent of mutant otolith-deficient mice has made it possible to isolate the relative contributions of the otoliths, the utricle and saccule. A number of studies have now indicated that the loss of otolithic function impairs normal spatial memory and also impairs the normal function of head direction cells in the thalamus and place cells in the hippocampus. Epidemiological studies have also provided evidence that spatial memory impairment with aging, may be linked to saccular function. The otoliths may be important in spatial cognition because of their evolutionary age as a sensory detector of orientation and the fact that velocity storage is important to the way that the brain encodes its place in space.
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