Evidence map›Paper›PMID 31680719›Full record

ReviewSeminars in interventional radiology2019

Individualized Ablation of Hepatocellular Carcinoma: Tailored Approaches across the Phenotype Spectrum.

Zlatko Devcic, Mohamed Elboraey, Lucas Vidal, Kabir Mody, Denise Harnois, Tushar Patel, Beau B Toskich

Abstract readReview
In one paragraph

Review in Seminars in interventional radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zlatko DevcicDivision of Interventional Radiology, Mayo Clinic Florida, Jacksonville, Florida.
Mohamed ElboraeyDivision of Interventional Radiology, Mayo Clinic Florida, Jacksonville, Florida.
Lucas VidalDepartment of Transplantation, Mayo Clinic Florida, Jacksonville, Florida.
Kabir ModyDivision of Oncology, Mayo Clinic Florida, Jacksonville, Florida.
Denise HarnoisDepartment of Transplantation, Mayo Clinic Florida, Jacksonville, Florida.
Tushar PatelDepartment of Transplantation, Mayo Clinic Florida, Jacksonville, Florida.
Beau B ToskichDivision of Interventional Radiology, Mayo Clinic Florida, Jacksonville, Florida.

Funding

Extracellular vesicle RNA signaling in liver tumor microenvironmentR01CA217833 · NCI · MAYO CLINIC JACKSONVILLE · PI PATEL, TUSHAR · 2018 to 2022
$1.8M
NCI NIH HHS R01 CA217833
6 · The paper itself

Abstract

Ablation is now recommended by international guidelines for the definitive treatment of hepatocellular carcinoma (HCC). Extensive clinical studies have demonstrated outcomes comparable to surgical resection with shorter hospital stays, decreased costs, and improved quality of life. Successful ablation requires complete treatment of both tumor and margin while preserving critical adjacent structures. HCC exhibits highly variable presentations in both anatomic involvement and biology which have significant implications on choice of ablative therapy. There are now abundant ablation modalities and adjunctive techniques which can be used to individualize ablation and maximize curative results. This article provides a patient-centered summary of approaches to HCC ablation in the context of patient performance, hepatic reserve, tumor phenotype and biology, intra- and extrahepatic anatomy, and ablation technology.

Indexed as

ablationhepatocellular carcinomalocoregional therapy

Identifiers

PMID31680719
PMCPMC6823046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.