Evidence map›Paper›PMID 31680699›Full record

ArticleExperimental mechanics2019

Two-Dimensional Culture Systems to Enable Mechanics-Based Assays for Stem Cell-Derived Cardiomyocytes.

J Notbohm, B N Napiwocki, W J deLange, A Stempien, A Saraswathibhatla, R J Craven, M R Salick, J C Ralphe, W C Crone

Abstract read
In one paragraph

Article in Experimental mechanics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Fabrication of Micropatterns of Aligned Collagen Fibrils.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Cardiac tissue engineering: Multiple approaches and potential applications.Frontiers in bioengineering and biotechnology · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J NotbohmDepartment of Engineering Physics, University of Wisconsin-Madison, Madison WI, USA.
B N NapiwockiDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison WI, USA.
W J deLangeDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
A StempienDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison WI, USA.
A SaraswathibhatlaDepartment of Engineering Physics, University of Wisconsin-Madison, Madison WI, USA.
R J CravenDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison WI, USA.
M R SalickWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison WI, USA.
J C RalpheDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
W C CroneDepartment of Engineering Physics, University of Wisconsin-Madison, Madison WI, USA.

Funding

Murine 3D Engineered Tissue Model of Human MYBPC3 MutationsR01HL107367 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI RALPHE, JOHN CARTER · 2011 to 2015
$1.8M
NHLBI NIH HHS R01 HL107367
6 · The paper itself

Abstract

Well-controlled 2D cell culture systems advance basic investigations in cell biology and provide innovative platforms for drug development, toxicity testing, and diagnostic assays. These cell culture systems have become more advanced in order to provide and to quantify the appropriate biomechanical and biochemical cues that mimic the milieu of conditions present

Indexed as

CardiomyocyteCell culture systemsDigital image correlationMicropatterningTraction force microscopy

Identifiers

PMID31680699
PMCPMC6824432

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.