Evidence map›Paper›PMID 31680527›Full record

ArticleOrganic letters2020

Daphneodorins A-C, Anti-HIV Gnidimacrin Related Macrocyclic Daphnane Orthoesters from

Kouharu Otsuki, Wei Li, Yoshihisa Asada, Chin-Ho Chen, Kuo-Hsiung Lee, Kazuo Koike

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Identification of Daphnane Diterpenoids fromPlants (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Lead/Drug Discovery from Natural Resources.Molecules (Basel, Switzerland) · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Daphnane-type diterpenes from genusChinese herbal medicines · 2021
    Review
  14. Anti-HIV Tigliane Diterpenoids fromJournal of natural products · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Kouharu OtsukiFaculty of Pharmaceutical Sciences , Toho University , Miyama 2-2-1 , Funabashi , Chiba 274-8510 , Japan.
Wei LiFaculty of Pharmaceutical Sciences , Toho University , Miyama 2-2-1 , Funabashi , Chiba 274-8510 , Japan.ORCID 0000-0003-4143-8597
Yoshihisa AsadaFaculty of Pharmaceutical Sciences , Toho University , Miyama 2-2-1 , Funabashi , Chiba 274-8510 , Japan.
Chin-Ho ChenSurgical Science, Department of Surgery , Duke University Medical Center , Durham , North Carolina 27710 , United States.ORCID 0000-0001-6880-2104
Kuo-Hsiung LeeNatural Products Research Laboratories, UNC Eshelman School of Pharmacy , University of North Carolina , Chapel Hill , North Carolina 27599 , United States.ORCID 0000-0002-6562-0070
Kazuo KoikeFaculty of Pharmaceutical Sciences , Toho University , Miyama 2-2-1 , Funabashi , Chiba 274-8510 , Japan.
Toho University · JPDuke Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

PLANT ANTIHIV AGENTSR01AI033066 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEE, KUO-HSIUNG · 1992 to 2018
$8.4M
NIAID NIH HHS R01 AI033066
6 · The paper itself

Abstract

Three novel gnidimacrin related macrocyclic daphnanes (GMDs), daphneodorins A-C (

Indexed as

Anti-HIV AgentsDaphneDose-Response Relationship, DrugHIV-1Macrocyclic CompoundsMicrobial Sensitivity TestsMolecular ConformationStructure-Activity RelationshipVirus ReplicationAnti-HIV AgentsMacrocyclic Compounds

Identifiers

PMID31680527
PMCPMC7437546
OpenAlexW2984077141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.