Evidence map›Paper›PMID 31680470›Full record

ArticleJournal of cellular and molecular medicine2020

Effect of (R)-salbutamol on the switch of phenotype and metabolic pattern in LPS-induced macrophage cells.

Shanping Wang, Fei Liu, Keai Sinn Tan, Hooi-Leng Ser, Loh Teng-Hern Tan, Learn-Han Lee, Wen Tan

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. BetaScandinavian journal of medicine & science in sports · 2022
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  10. BetaBiomedicines · 2024
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  12. Ketone bodies as chemical signals for the immune system.American journal of physiology. Cell physiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shanping WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.ORCID 0000-0003-1313-369X
Fei LiuInstitute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Keai Sinn TanInstitute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Hooi-Leng SerInstitute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Loh Teng-Hern TanInstitute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Learn-Han LeeNovel Bacteria and Drug Discovery (NBDD) Research Group, Microbiome and Bioresource Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.
Wen TanInstitute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Monash University Malaysia · MYGuangdong University of Technology · CNSouth China University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence demonstrates that M1 macrophage polarization promotes inflammatory disease. Here, we discovered that (R)-salbutamol, a β

Indexed as

Cell PolarityAdrenergic beta-2 Receptor AgonistsAlbuterolAnimalsCytokinesGene Expression RegulationGlycolysisLipopolysaccharidesMacrophage ActivationMacrophagesMetabolomeMiceNitric OxidePhenotypeRAW 264.7 CellsReactive Oxygen SpeciesAdrenergic beta-2 Receptor AgonistsAlbuterolCytokinesLipopolysaccharidesNitric OxideReactive Oxygen Speciescell metabolomicsECARinflammationmacrophage polarizationOCR

Identifiers

PMID31680470
PMCPMC6933346
OpenAlexW2984286047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.