Evidence map›Paper›PMID 31680356›Full record

ArticlePhytotherapy research : PTR2020

Torsten Grothe, Franziska Wandrey, Cornelia Schuerch

Open access · hybridAbstract read
In one paragraph

Article in Phytotherapy research : PTR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Effect of applyingBioscience of microbiota, food and health · 2024
    Article
  7. Article
  8. Phytotherapy research : PTR · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Torsten GrotheMibelle Group Biochemistry, Mibelle AG, Bolimattstrasse 1, 5033, Buchs, AG, Switzerland.ORCID https://orcid.org/0000-0003-3298-4924
Franziska WandreyMibelle Group Biochemistry, Mibelle AG, Bolimattstrasse 1, 5033, Buchs, AG, Switzerland.
Cornelia SchuerchMibelle Group Biochemistry, Mibelle AG, Bolimattstrasse 1, 5033, Buchs, AG, Switzerland.
Sophia Genetics (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair loss affects millions of people worldwide, but currently available treatment options are often dissatisfying due to side effects or limited efficacy. Pea sprout extract has been shown to improve hair density when applied topically, but its mode of action and effectiveness upon oral administration remain unknown. Our study has now shown that the application of a fluid containing 2% pea sprout extract on a defined scalp zone of 10 volunteers enhances the expression of defined genes relevant for hair, namely fibroblast growth factor-7 (FGF7) and noggin, by 56 and 85%, respectively. Additionally, a subsequent pilot nutrition intervention study in 21 volunteers proved that pea sprout extract is also effective when consumed as dietary supplement. The daily intake of 100 mg pea sprout extract (AnaGain™ Nu) for 8 weeks significantly reduced hair loss already after 28 days of treatment (p < 0.002). No adverse events were reported. Consequently, pea sprout extract may be an effective means to safely promote hair growth and reduce hair loss in individuals experiencing excessive hair shedding.

Indexed as

Dietary SupplementsAdministration, CutaneousAdministration, OralAdultAlopeciaCarrier ProteinsFemaleFibroblast Growth Factor 7Gene Expression RegulationHairHumansMaleMiddle AgedNoggin ProteinPilot ProjectsPisum sativumCarrier ProteinsFGF7 protein, humanFibroblast Growth Factor 7Noggin ProteinPlant ExtractsFGF7hair growthhair lossnogginpea sprout extract

Identifiers

PMID31680356
PMCPMC8246764
OpenAlexW2987611519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.