Evidence map›Paper›PMID 31679841›Full record

ReviewTrends in biochemical sciences2020

Bacterial RNA Degradosomes: Molecular Machines under Tight Control.

Alejandro Tejada-Arranz, Valérie de Crécy-Lagard, Hilde de Reuse

Open access · greenAbstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 64 citations in OpenAlex.

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  19. SUV3 Helicase and Mitochondrial Homeostasis.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Alejandro Tejada-ArranzHelicobacter Pathogenesis Unit, Department of Microbiology, Institut Pasteur, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA; University of Florida Genetics Institute, Gainesville, FL, USA.
Hilde de ReuseHelicobacter Pathogenesis Unit, Department of Microbiology, Institut Pasteur, Paris, France. Electronic address: hdereuse@pasteur.fr.
Délégation Paris 7 · FRInstitut Pasteur · FRUniversity of Florida · US

Funding

Synthesis and function of Queuosine in BacteriaR01GM070641 · NIGMS · UNIVERSITY OF FLORIDA · PI DE CRECY-LAGARD, VALERIE A · 2006 to 2023
$5.3M
NIGMS NIH HHS R01 GM070641
6 · The paper itself

Abstract

Bacterial RNA degradosomes are multienzyme molecular machines that act as hubs for post-transcriptional regulation of gene expression. The ribonuclease activities of these complexes require tight regulation, as they are usually essential for cell survival while potentially destructive. Recent studies have unveiled a wide variety of regulatory mechanisms including autoregulation, post-translational modifications, and protein compartmentalization. Recently, the subcellular organization of bacterial RNA degradosomes was found to present similarities with eukaryotic messenger ribonucleoprotein (mRNP) granules, membraneless compartments that are also involved in mRNA and protein storage and/or mRNA degradation. In this review, we present the current knowledge on the composition and targets of RNA degradosomes, the most recent developments regarding the regulation of these machineries, and their similarities with the eukaryotic mRNP granules.

Indexed as

EndoribonucleasesMultienzyme ComplexesPolyribonucleotide NucleotidyltransferaseRNA, BacterialRNA HelicasesdegradosomeEndoribonucleasesMultienzyme ComplexesPolyribonucleotide NucleotidyltransferaseRNA, BacterialRNA Helicasescompartmentalizationmembraneless organellesmRNP granulespost-transcriptional regulationRNA degradationRNA degradosomeRNA maturation

Identifiers

PMID31679841
PMCPMC6958999
OpenAlexW2986576781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.