Evidence map›Paper›PMID 31679181›Full record

ArticleThoracic cancer2019

Safety and clinical outcomes of computed tomography-guided percutaneous microwave ablation in patients aged 80 years and older with early-stage non-small cell lung cancer: A multicenter retrospective study.

Xiaoying Han, Xia Yang, Guanghui Huang, Chunhai Li, Licheng Zhang, Yuanxun Qiao, Chuntang Wang, Yuting Dong, Xiangming Chen, Qingliang Feng and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Efficacy and safety of CT-guided microwave ablation for stage I non-small cell lung cancer in elderly patients.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. CT-based radiomics models may predict the early efficacy of microwave ablation in malignant lung tumors.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xiaoying HanDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.ORCID 0000-0001-5568-2326
Xia YangDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Guanghui HuangDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Chunhai LiShandong University Qilu Hospital, Jinan, China.
Licheng Zhang960 Military Hospital of China, Taian, China.
Yuanxun QiaoTaian Hospital of Traditional Chinese Medicine, Dezhou, China.
Chuntang WangThe Second People Hospital of Dezhou, Liaocheng, China.
Yuting DongDezhou People's Hospital, Dezhou, China.
Xiangming ChenTaishan Hospital affiliated to Taishan Medical College, Taian, China.
Qingliang FengLiaocheng Tumor Hospital, Liaocheng, China.
Chuandai WangFeicheng Hospital of Traditional Chinese Medicine, Taian, China.
Zhenhua RongThe People's Hospital of Cao County, Heze, China.
Kun DingShouguang Hospital of Traditional Chinese Medicine, Weifang, China.
Zhigang WeiDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Yang NiDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Jiao WangDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Wenhong LiDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Min MengDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, China.
Xin YeLiaocheng Tumor Hospital, Liaocheng, China.ORCID 0000-0002-2798-8923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have documented the therapeutic value of computed tomography (CT)-guided percutaneous microwave ablation (MWA) for early-stage non-small cell lung cancer (NSCLC). However, few studies have focused on patients aged 80 years and older. This retrospective study aimed to evaluate the safety and clinical outcomes of CT-guided percutaneous MWA in patients aged 80 years and older with early-stage peripheral NSCLC.

methodsA retrospective analysis of 63 patients aged 80 years and older with cT1a-2bN0M0 peripheral NSCLC who underwent CT-guided percutaneous MWA was performed between January 2008 and January 2018 at 11 hospitals in Shandong Province, China.

resultsThe median follow-up time was 21.0 months. The overall median survival time was 50 months. The cancer-specific median survival time was not reached in five years. The one-, two-, three-, four-, and five-year overall survival rates were 97.1%, 92.6%, 63.4%, 54.4%, and 32.6%, respectively. The one-, two-, and three-year cancer-specific survival (CSS) rates were 97.9%, 97.9%, and 69.4%, respectively. The four- and five-year CSS rates were not achieved. A total of 14 patients (22.2%) had local progression. The one-, two-, three-, four-, and five-year local control rates were 88.8%, 78.8%, 70.3%, 63.9%, and 63.9%, respectively. The mortality rate was 0% within 30 days after the procedure. Major complications included pneumothorax requiring drainage (21.1%), pulmonary infection (4.2%), and pleural effusions requiring drainage (2.8%).

conclusionsCT-guided percutaneous MWA is a safe and effective modality for treating patients aged 80 years and older with early-stage peripheral NSCLC.

Indexed as

AgedAged, 80 and overCarcinoma, Non-Small-Cell LungCatheter AblationComorbidityFemaleHumansKaplan-Meier EstimateLung NeoplasmsMaleMicrowavesPrognosisRetrospective StudiesSurgery, Computer-AssistedTomography, X-Ray ComputedTreatment OutcomeMicrowave ablationnon-small cell lung cancerolder patients

Identifiers

PMID31679181
PMCPMC6885429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.