Evidence map›Paper›PMID 31679123›Full record

ArticleInflammopharmacology2020

Anti-inflammatory and antinociceptive effects of an ethanol extract from Senna septemtrionalis.

Víctor Ermilo Arana-Argáez, Fabiola Domínguez, Diego A Moreno, Mario Alberto Isiordia-Espinoza, Julio Cesar Lara-Riegos, Emanuel Ceballos-Góngora, Juan Ramón Zapata-Morales, Lorenzo Franco-de la Torre, Sergio Sánchez-Enríquez, Angel Josabad Alonso-Castro

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Antioxidant and Anti-Inflammatory Activities of Methanol Extract ofInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Víctor Ermilo Arana-ArgáezFacultad de Química, Universidad Autónoma de Yucatán, Calle 43, Calle 90 613 x, Inalámbrica, 97069, Mérida, Yucatán, Mexico.
Fabiola DomínguezLaboratorio de Biotecnología de Productos Naturales, Centro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Federal Atlixco-Metepec, C.P. 74360, Metepec, Puebla, Mexico.
Diego A MorenoPhytochemistry and Healthy Foods Lab., Food Science and Technology Department, CEBAS-CSIC, Campus Universitario Espinardo - 25, 30100, Espinardo, Murcia, Spain.
Mario Alberto Isiordia-EspinozaDepartamento de Clínicas, División de Ciencias Biomédicas, Centro Universitario de los Altos, Universidad de Guadalajara, Av. Rafael Casillas Aceves 1200, 47620, Tepatitlán de Morelos, Jalisco, Mexico.
Julio Cesar Lara-RiegosFacultad de Química, Universidad Autónoma de Yucatán, Calle 43, Calle 90 613 x, Inalámbrica, 97069, Mérida, Yucatán, Mexico.
Emanuel Ceballos-GóngoraFacultad de Química, Universidad Autónoma de Yucatán, Calle 43, Calle 90 613 x, Inalámbrica, 97069, Mérida, Yucatán, Mexico.
Juan Ramón Zapata-MoralesDivisión de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, C.P. 36050, Guanajuato, Gto, Mexico.
Lorenzo Franco-de la TorreDepartamento de Clínicas, División de Ciencias Biomédicas, Centro Universitario de los Altos, Universidad de Guadalajara, Av. Rafael Casillas Aceves 1200, 47620, Tepatitlán de Morelos, Jalisco, Mexico.
Sergio Sánchez-EnríquezDepartamento de Clínicas, División de Ciencias Biomédicas, Centro Universitario de los Altos, Universidad de Guadalajara, Av. Rafael Casillas Aceves 1200, 47620, Tepatitlán de Morelos, Jalisco, Mexico.
Angel Josabad Alonso-CastroDivisión de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, C.P. 36050, Guanajuato, Gto, Mexico. angeljosabad@ugto.mx.ORCID http://orcid.org/0000-0003-2660-8156
Autonomous University of Yucatán · MXUniversidad de Guadalajara · MXUniversidad de Guanajuato · MXCentro de Edafología y Biología Aplicada del Segura · ESMexican Social Security Institute · MX

Funding

Secretaría de Educación Pública 511-6/18/9169Universidad de Guanajuato CIIC 67/2019
6 · The paper itself

Abstract

Senna septemtrionalis (Viv.) H.S. Irwin & Barneby (Fabaceae) is a medicinal plant used as a folk remedy for inflammation and pain. The objective of this study was to evaluate the anti-inflammatory and antinociceptive actions of an ethanol extract of Senna septemtrionalis aerial parts (SSE). The in vitro anti-inflammatory effects of SSE were assessed using LPS-stimulated macrophages and the subsequent quantification of the levels of cytokines (IL-6, IL-1β, and TNF-α) with ELISA kits, nitric oxide (NO), and hydrogen peroxide (H

Indexed as

AnalgesicsAnimalsAnti-Inflammatory AgentsDisease Models, AnimalDose-Response Relationship, DrugEdemaEthanolHydrogen PeroxideInflammationInhibitory Concentration 50MacrophagesMice, Inbred BALB CPainPlant ExtractsSenna PlantAnalgesicsAnti-Inflammatory AgentsEthanolHydrogen PeroxidePlant ExtractsAnti-inflammatoryAntinociceptiveMedicinal plantSenna septemtrionalis

Identifiers

PMID31679123
OpenAlexW2984598539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.