Evidence map›Paper›PMID 31679105›Full record

ArticleJournal of muscle research and cell motility2020

Effects of S-glutathionylation on the passive force-length relationship in skeletal muscle fibres of rats and humans.

Daiki Watanabe, Cedric R Lamboley, Graham D Lamb

Abstract read
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In one paragraph

Article in Journal of muscle research and cell motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Influence of neuromuscular transmission and NaJournal of muscle research and cell motility · 2025
    Article
  3. Article
  4. Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx).Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daiki WatanabeDepartment of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne, Australia. dwatanabe@hiroshima-u.ac.jp.
Cedric R LamboleyDepartment of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne, Australia.
Graham D LambDepartment of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne, Australia.
La Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effect of S-glutathionylation on passive force in skeletal muscle fibres, to determine whether activity-related redox reactions could modulate the passive force properties of muscle. Mechanically-skinned fibres were freshly obtained from human and rat muscle, setting sarcomere length (SL) by laser diffraction. Larger stretches were required to produce passive force in human fibres compared to rat fibres, but there were no fibre-type differences in either species. When fibres were exposed to glutathione disulfide (GSSG; 20 mM, 15 min) whilst stretched (at a SL where passive force reached ~ 20% of maximal Ca

Indexed as

AnimalsHumansMuscle Fibers, SkeletalProtein SRatsProtein SMuscle elasticityOxidative stressPassive forceSkinned fibreTitin

Identifiers

PMID31679105
OpenAlexW2989498133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.