Evidence map›Paper›PMID 31679084›Full record

ArticleMolecular diversity2020

Synthesis of new pyrimidine-containing compounds: 5-(2-(alkylamino)-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives.

Khudaidad Kochia, Mohammad Bayat, Shima Nasri, Aref Mohammadi

Abstract read
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In one paragraph

Article in Molecular diversity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Khudaidad KochiaDepartment of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran.
Mohammad BayatDepartment of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran. bayat_mo@yahoo.com.ORCID http://orcid.org/0000-0002-5235-1203
Shima NasriDepartment of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran.
Aref MohammadiDepartment of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran.
Imam Khomeini International University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the one-pot reaction between primary amines, 1,1-bis-(methylthio)-2-nitroethene, ninhydrin, and barbituric acid as an enolizable C-H-activated compound provides a simple method for the preparation of 5-(2-(alkylamino)-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives with potential synthetic and pharmacological interest. This reaction shows attractive characteristics, such as substrate availability, good yields, existence of numerous hydrogen-bonding possibilities in product, and its mild conditions in ethanol media.

Indexed as

AminesBarbituratesHydrogen BondingNinhydrinPyrimidinesAminesBarbituratesbarbituric acidNinhydrinpyrimidinePyrimidinesBarbituric acidIndeneNinhydrinNitroketene dithioacetalsPyrimidine

Identifiers

PMID31679084
OpenAlexW2986421217

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.