Evidence map›Paper›PMID 31678033›Full record

ArticleThe Lancet. Neurology2020

Increased striatal dopamine in carriers of GBA mutations: compensation or epiphenomenon?

Nicolaas I Bohnen, Roger L Albin

Open access · greenAbstract readComment
In one paragraph

Article in The Lancet. Neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicolaas I BohnenDepartment of Radiology, Ann Arbor, MI 48109, USA; Department of Neurology, University of Michigan, University of Michigan Udall Center, and VA Ann Arbor Healthcare System, Ann Arbor, MI 48109, USA. Electronic address: nbohnen@umich.edu.
Roger L AlbinDepartment of Neurology, University of Michigan, University of Michigan Udall Center, and VA Ann Arbor Healthcare System, Ann Arbor, MI 48109, USA.
University of Michigan–Ann Arbor · US

Funding

Tomography and Data AnalysisP01NS015655 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOEPPE, ROBERT A · 1985 to 2012
$13.0M
Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
Modulation of GABA-A Receptors and Axial Motor Impairments in Parkinson DiseaseR01NS099535 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOHNEN, NICOLAAS IDA · 2017 to 2020
$2.1M
Amyloidopathy, cholinopathy, dopamine responsiveness and freezing of gait in PDI01RX001631 · VA · VETERANS HEALTH ADMINISTRATION · PI BOHNEN, NICOLAAS IDA · 2016 to 2020
–
NINDS NIH HHS P01 NS015655NINDS NIH HHS P50 NS091856NINDS NIH HHS R01 NS099535RRD VA I01 RX001631
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DopamineHeterozygoteMutationDopamine

Identifiers

PMID31678033
PMCPMC6924570
OpenAlexW2982625546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.