ArticleEnvironmental pollution (Barking, Essex : 1987)2020
Glyphosate exposures and kidney injury biomarkers in infants and young children.
Article in Environmental pollution (Barking, Essex : 1987), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 80 citations in OpenAlex.
- Beyond genetics: how environmental stressors drive pediatric hypertension risk.Pediatric nephrology (Berlin, Germany) · 2026Review
- Environmental exposures and pediatric kidney health.Pediatric research · 2026Review
- Evidence-Based Assessment of Pesticide-Related Nephrotoxicity: Clinical Outcomes, Experimental Data, and Molecular Signatures.International journal of molecular sciences · 2026Review
- Measured exposures to glyphosate in applicators and the general population: an updated review of the scientific literature since 2020.Pest management science · 2025Review
- Sociodemographic and dietary determinants of glyphosate exposure in a NYC-based pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Relationship of urinary glyphosate concentrations with glycosylated hemoglobin and diabetes in US adults: a cross-sectional study.BMC public health · 2024Article
- Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study.Scientific reports · 2024Article
- Glyphosate as a Food Contaminant: Main Sources, Detection Levels, and Implications for Human and Public Health.Foods (Basel, Switzerland) · 2024Article
- Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication.ACS pharmacology & translational science · 2024Review
- Exploring the Utility of Urinary Creatinine Adjustment for KIM-1, NGAL, and Cystatin C for the Assessment of Kidney Function: Insights from the C-KidnEES Cohort.Children (Basel, Switzerland) · 2023Article
- Impact of glyphosate (RoundupGut microbes · 2023Review
- Frequency of urinary pesticides in children: a scoping review.Frontiers in public health · 2023Article
- Impact of Glyphosate on the Development of Insulin Resistance in Experimental Diabetic Rats: Role of NFκB Signalling Pathways.Antioxidants (Basel, Switzerland) · 2022Article
- Exposure to glyphosate in the United States: Data from the 2013-2014 National Health and Nutrition Examination Survey.Environment international · 2022Article
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- Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers.Environmental science and pollution research international · 2022Article
- A Method for the Analysis of Glyphosate, Aminomethylphosphonic Acid, and Glufosinate in Human Urine Using Liquid Chromatography-Tandem Mass Spectrometry.International journal of environmental research and public health · 2022Article
- Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part I-Lessons Learned on Polycyclic Aromatic Hydrocarbons, Metals, Metalloids, and Pesticides.Molecules (Basel, Switzerland) · 2021Review
- Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study.Environment international · 2021Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
The goal of this study was to assess biomarkers of exposure to glyphosate and assess potential associations with renal function in children. Glyphosate is used ubiquitously in agriculture worldwide. While previous studies have indicated that glyphosate may have nephrotoxic effects, few have examined potential effects on kidney function in children. We leveraged three cohorts across different phases of child development and measured urinary levels of glyphosate. We evaluated associations of glyphosate with three biomarkers of kidney injury: albuminuria (ACR), neutrophil gelatinase-associated lipocalin (NGAL), and kidney injury marker 1 (KIM-1). Multivariable regression analyses examined associations of glyphosate with kidney injury biomarkers controlling for covariates. We identified glyphosate in 11.1% of the total participants. The herbicide was detected more frequently in the neonate population (30%). Multivariable regression models failed to identify significant associations of log-transformed glyphosate with any of the kidney injury biomarkers, controlling for covariates age, sex, and maternal education. While we confirm detectability of glyphosate in children's urine at various ages and stages of life, there is no evidence in this study for renal injury in children exposed to low levels of glyphosate. Further studies of larger sample size are indicated to better understand putative deleterious effects of the herbicide after different levels of exposure.
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