SynthesisNeuroImage. Clinical2019
Properties of cross-modal occipital responses in early blindness: An ALE meta-analysis.
Synthesis in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Cognition, body, and mind: A three-in-one coordinate-based fMRI meta-analysis on cognitive, physical, and meditative trainings.Human brain mapping · 2023Pooled it
- Relational vs representational social cognitive processing: a coordinate-based meta-analysis of neuroimaging data.Social cognitive and affective neuroscience · 2023Pooled it
- Neural substrates of spatial processing and navigation in blindness: An activation likelihood estimation meta-analysis.Frontiers in neuroscience · 2022Pooled it
- Social cognition in the blind brain: A coordinate-based meta-analysis.Human brain mapping · 2021Pooled it
- Cross-modal plasticity in a blind jazz pianist and prodigy.Neuroimage. Reports · 2026Article
- Decoding Post-Stroke Cognitive Impairment After Acute Basal Ganglia Infarction: The Synergistic Role of Functional Segregation and Integration in an SVM fMRI Framework.CNS neuroscience & therapeutics · 2026Article
- Adjectives improve color perception in visually impaired people through multisensory stimulation.Frontiers in psychology · 2026Article
- Structurally constrained functional connectivity reveals efficient visuomotor decision-making mechanisms in action video gamers.Scientific reports · 2025Article
- Penetrance of Neurodevelopmental Copy Number Variants Is Associated With Variations in Cortical Morphology.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Investigating visual perception abilities in flight cadets: the crucial role of the lingual gyrus and precuneus.Frontiers in neuroscience · 2025Article
- Alterations of interhemispheric functional connectivity in patients with hypertensive retinopathy using voxel-mirrored homotopic connectivity: a resting state fMRI study.International journal of ophthalmology · 2025Article
- Visual stimulation rehabilitation for cortical blindness after vertebral artery interventional surgery: A case report and literature review.International journal of surgery case reports · 2023Article
- Similar object shape representation encoded in the inferolateral occipitotemporal cortex of sighted and early blind people.PLoS biology · 2023Article
- Abnormal brain spontaneous activity in major depressive disorder adolescents with non-suicidal self injury and its changes after sertraline therapy.Frontiers in psychiatry · 2023Article
- Alteration of Degree Centrality in Adolescents With Early Blindness.Frontiers in human neuroscience · 2022Article
- Disruption of Cerebellar-Cerebral Functional Connectivity in Temporal Lobe Epilepsy and the Connection to Language and Cognitive Functions.Frontiers in neuroscience · 2022Article
- Watershed Brain Regions for Characterizing Brand Equity-Related Mental Processes.Brain sciences · 2021Article
- [Effects of olfactory deprivation on action potential and ankyrin-G expression in glutamatergic neurons in the barrel cortex of mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Affective face biases in visual and prefrontal cortex measured with visual entrainment.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cross-modal occipital responses appear to be essential for nonvisual processing in individuals with early blindness. However, it is not clear whether the recruitment of occipital regions depends on functional domain or sensory modality. The current study utilized a coordinate-based meta-analysis to identify the distinct brain regions involved in the functional domains of object, spatial/motion, and language processing and the common brain regions involved in both auditory and tactile modalities in individuals with early blindness. Following the PRISMA guidelines, a total of 55 studies were included in the meta-analysis. The specific analyses revealed the brain regions that are consistently recruited for each function, such as the dorsal fronto-parietal network for spatial function and ventral occipito-temporal network for object function. This is consistent with the literature, suggesting that the two visual streams are preserved in early blind individuals. The contrast analyses found specific activations in the left cuneus and lingual gyrus for language function. This finding is novel and suggests a reverse hierarchical organization of the visual cortex for early blind individuals. The conjunction analyses found common activations in the right middle temporal gyrus, right precuneus and a left parieto-occipital region. Clinically, this work contributes to visual rehabilitation in early blind individuals by revealing the function-dependent and sensory-independent networks during nonvisual processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.