Evidence map›Paper›PMID 31677552›Full record

ArticleRedox biology2020

Ferritin is regulated by a neuro-intestinal axis in the nematode Caenorhabditis elegans.

Leonor Romero-Afrima, Veronica Zelmanovich, Zohar Abergel, Binyamin Zuckerman, Maayan Shaked, Rachel Abergel, Leonid Livshits, Yoav Smith, Einav Gross

Open access · goldAbstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it

0cells of the map it votes in

9citing papers in PubMed

0.6field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

Host Oxidative Response Capacity Determines Longevity Outcomes of Microbial Interventions.Aging cell · 2026
Article
Forward genetics ineLife · 2025
Article
Ferric Uptake Regulator Contributes toMicroorganisms · 2025
Article
Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans.PloS one · 2024
Article
Role of ferroptosis in effects of anesthetics on multiple organ diseases: A literature review.Heliyon · 2023
Review
Distinct designer diamines promote mitophagy, and thereby enhance healthspan inAutophagy · 2023
Article
Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans.PLoS genetics · 2021
Article
Structural and functional relationship of mammalian and nematode ferritins.Biotechnologia · 2021
Review
Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response.GeroScience · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Leonor Romero-AfrimaDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Veronica ZelmanovichDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Zohar AbergelDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Binyamin ZuckermanDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Maayan ShakedDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Rachel AbergelDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Leonid LivshitsDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel.

Yoav SmithGenomic Data Analysis Unit, The Hebrew University - Hadassah Medical School, The Hebrew University of Jerusalem, 91120, Jerusalem, Israel.

Einav GrossDept. of Biochemistry and Molecular Biology, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Kerem. P.O. Box 12271, Jerusalem, 9112102, Israel. Electronic address: einavg@ekmd.huji.ac.il.

Hebrew University of Jerusalem · IL

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026

$7.5M

NIH HHS P40 OD010440

6 · The paper itself

Abstract

Iron is vital for the life of most organisms. However, when dysregulated, iron can catalyze the formation of oxygen (O

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell HypoxiaFerritinsGene Expression RegulationHypoxia-Inducible Factor 1, alpha SubunitIntestinal MucosaIronNervous SystemNeuropeptidesOxygenCaenorhabditis elegans ProteinsFerritinsHypoxia-Inducible Factor 1, alpha SubunitIronNeuropeptidesOxygenCaenorhabditis elegansEGL-9Ferritinftn-1HIF-1HypoxiaOxygen sensing neuronsSoluble guanylate cyclasesVHL-1

Identifiers

PMID31677552

DOI10.1016/j.redox.2019.101359

PMCPMC6920132

OpenAlexW2981826368

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.