Evidence map›Paper›PMID 31677162›Full record

ReviewThe British journal of dermatology2020

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group.

H Alexander, A S Paller, C Traidl-Hoffmann, L A Beck, A De Benedetto, S Dhar, G Girolomoni, A D Irvine, P Spuls, J Su and 6 more

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 3 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 3 syntheses or guidelines pooled it, 207 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Phototherapy for atopic eczema.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Review
  5. Observational
  6. Atopic dermatitis.Nature reviews. Disease primers · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Mapping the Burden and Risk Factors of Allergic Diseases and Asthma Among Aboriginal and Torres Strait Islander People: A Scoping Review.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  12. Article
  13. Article
  14. Association betweenFrontiers in medicine · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Evaluation of the Dermatoprotective Properties of Clinopodium nepeta and Thymus vulgaris Essential Oils: Phytochemical Analysis, Anti-Elastase, Anti-Tyrosinase, Photoprotective Activities, and Antimicrobial Potential Against Dermatopathogenic Strains.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2025
    Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 10 countries.

H AlexanderUnit for Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, SE1 7EH, U.K.ORCID 0000-0002-0241-5408
A S PallerDepartments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, U.S.A.ORCID 0000-0001-6187-6549
C Traidl-HoffmannChair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Augsburg, Germany.ORCID 0000-0001-5085-5179
L A BeckDepartment of Dermatology, University of Rochester Medical Center, Rochester, NY, U.S.A.ORCID 0000-0002-8452-667X
A De BenedettoDepartment of Dermatology, College of Medicine, University of Florida, Gainesville, FL, U.S.A.
S DharDepartment of Pediatric Dermatology, Institute of Child Health, Kolkata, India.ORCID 0000-0002-9304-2212
G GirolomoniDepartment of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, Italy.ORCID 0000-0001-8548-0493
A D IrvineDepartment of Clinical Medicine, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-9048-2044
P SpulsDepartment of Dermatology, Amsterdam Public Health, Infection and Immunity, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-6035-2863
J SuDepartments of Dermatology and Paediatrics, Murdoch Children's Research Institute, University of Melbourne and Monash University, Eastern Health, Melbourne, VIC, Australia.ORCID 0000-0002-4021-5423
J P ThyssenDepartment of Dermatology and Allergy, Herlev-Gentofte Hospital, Hellerup, Denmark.ORCID 0000-0003-3770-1743
C VestergaardDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-6485-3158
T WerfelDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-7957-4917
A WollenbergDepartment of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany.ORCID 0000-0003-0177-8722
M DeleuranDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-0593-9925
C FlohrUnit for Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, SE1 7EH, U.K.ORCID 0000-0003-4884-6286
Aarhus University Hospital · DKGuy's and St Thomas' NHS Foundation Trust · GBAmsterdam University Medical Centers · NLEastern Health · AUGentofte Hospital · DKHelmholtz Zentrum München · DEInstitute of Child Health · INLudwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DENorthwestern University · USTrinity College Dublin · IEUniversity of Florida · USUniversity of Rochester Medical Center · USUniversity of Verona · IT

Funding

Department of Health CDF-2014-07-037NIHR Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London
6 · The paper itself

Abstract

Patients with atopic dermatitis (AD) have an increased risk of bacterial skin infections, which cause significant morbidity and, if untreated, may become systemic. Staphylococcus aureus colonizes the skin of most patients with AD and is the most common organism to cause infections. Overt bacterial infection is easily recognized by the appearance of weeping lesions, honey-coloured crusts and pustules. However, the wide variability in clinical presentation of bacterial infection in AD and the inherent features of AD - cutaneous erythema and warmth, oozing associated with oedema, and regional lymphadenopathy - overlap with those of infection, making clinical diagnosis challenging. Furthermore, some features may be masked because of anatomical site- and skin-type-specific features, and the high frequency of S. aureus colonization in AD makes positive skin swab culture of suspected infection unreliable as a diagnostic tool. The host mechanisms and microbial virulence factors that underlie S. aureus colonization and infection in AD are incompletely understood. The aim of this article is to present the latest evidence from animal and human studies, including recent microbiome research, to define the clinical features of bacterial infections in AD, and to summarize our current understanding of the host and bacterial factors that influence microbial colonization and virulence.

Indexed as

Dermatitis, AtopicEczemaStaphylococcal InfectionsStaphylococcal Skin InfectionsAnimalsHumansSkinStaphylococcus aureus

Identifiers

PMID31677162
PMCPMC7317931
OpenAlexW2983911779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.