Evidence map›Paper›PMID 31677159›Full record

ArticleInternational journal of cancer2020

Abdominal and gluteofemoral size and risk of liver cancer: The liver cancer pooling project.

Andrea A Florio, Peter T Campbell, Xuehong Zhang, Anne Zeleniuch-Jacquotte, Jean Wactawski-Wende, Stephanie A Smith-Warner, Rashmi Sinha, Tracey G Simon, Howard D Sesso, Catherine Schairer and 29 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. PNPLA3, Obesity, and Heavy Alcohol Use in Cirrhosis Patients May Exert a Synergistic Increase Hepatocellular Carcinoma Risk.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  9. Article
  10. Review
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  12. Review
  13. Review
  14. Article
  15. Article
  16. Dose-Response Association between Adiposity and Liver Cancer Incidence: A Prospective Cohort Study among Non-Smoking and Non-Alcohol-Drinking Chinese Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  17. Review
  18. Epidemiology of Hepatocellular Carcinoma.Hepatology (Baltimore, Md.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 16 institutions in 4 countries.

Andrea A FlorioDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Peter T CampbellBehavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA.
Xuehong ZhangChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA.
Anne Zeleniuch-JacquotteDepartment of Population Health, New York University School of Medicine, New York, NY.
Jean Wactawski-WendeDepartment of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY.
Stephanie A Smith-WarnerDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Rashmi SinhaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Tracey G SimonDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Howard D SessoDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Catherine SchairerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0001-7671-4972
Lynn RosenbergSlone Epidemiology Center, Boston University, Boston, MA.
Thomas E RohanDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY.
Kim RobienDepartment of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, DC.
Andrew G RenehanFaculty Institute of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Mark P PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0003-1177-3108
Jenny N PoynterDivision of Pediatric Epidemiology and Clinical Research and Masonic Cancer Center, University of Minnesota, Minneapolis, MN.ORCID 0000-0002-8460-3938
Julie R PalmerSlone Epidemiology Center, Boston University, Boston, MA.
Christina C NewtonBehavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA.
Yunxia LuDepartment of Population Health and Disease Prevention, Program in Public Health, University of California Irvine, Irvine, CA.
Martha S LinetDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
I-Min LeeDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Jill KoshiolDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Cari M KitaharaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0001-6416-4432
Victoria A KirshEpidemiology Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Jonathan N HofmannDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Barry I GraubardDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Edward GiovannucciDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
John M GazianoDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA.
Susan M GapsturBehavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA.
Neal D FreedmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Jane DemuthInformation Management Services Inc, Silver Spring, MD.
Dawn Q ChongDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
Andrew T ChanChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA.
Julie E BuringDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Patrick T BradshawDivision of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, CA.
Laura E Beane FreemanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Katherine A McGlynnDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0003-2329-9933
Jessica L PetrickDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.ORCID 0000-0001-6580-450X
National Cancer Institute · USBrigham and Women's Hospital · USAmerican Cancer Society · USBoston University · USHarvard University · USAlbert Einstein College of Medicine · USInformation Management Services · USMilken Institute · USNational Cancer Centre Singapore · SGNew York University · USUniversity at Buffalo, State University of New York · USUniversity of California, Berkeley · USUniversity of California, Irvine · USUniversity of Manchester · GBUniversity of Minnesota Medical Center · USUniversity of Toronto · CA

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSNER, BERNARD A · 2000 to 2019
$77.8M
Tissue and Pathology ResourcesP50CA127003 · NCI · DANA-FARBER CANCER INST · PI BASS, ADAM JOEL · 2007 to 2023
$33.2M
Women's Health Study: Continued Follow-upR01CA047988 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., LEE, I-MIN · 1991 to 2014
$28.2M
RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZELIKOFF, JUDITH TERRY · 1985 to 2020
$26.1M
A Follow-up Study for Causes of Cancer in Black WomenU01CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kimberly A. Bertrand, Yvette C Cozier · 2017 to 2026
$24.0M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
FOLLOW-UP STUDY FOR CAUSES OF ILLNESS IN BLACK WOMENR01CA058420 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 1999 to 2013
$20.7M
Studies of Rare CancersZIACP010158 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MCGLYNN, KATHERINE · 2009 to 2025
$19.1M
Cancer Epidemiology Cohort in Male Health ProfessionalsU01CA167552 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Lorelei Mucci, Walter C. Willett · 2017 to 2026
$17.0M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
EPIDEMIOLOGY OF CANCER IN A COHORT OF OLDER WOMENR01CA039742 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LAZOVICH, DEANN · 1985 to 2014
$8.0M
Intramural NIH HHS ZIA CP010158NCI NIH HHS K07 CA188126NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA016087NCI NIH HHS P50 CA127003NCI NIH HHS R01 CA039742NCI NIH HHS R01 CA047988NCI NIH HHS R01 CA058420NCI NIH HHS U01 CA164974NCI NIH HHS U01 CA167552NCI NIH HHS U01 CA182913NCI NIH HHS UM1 CA167552NCI NIH HHS UM1 CA182934NCI NIH HHS UM1 CA186107NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNHLBI NIH HHS R01 HL043851NHLBI NIH HHS R01 HL080467NHLBI NIH HHS RC1 HL099355NIDDK NIH HHS K24 DK098311NIEHS NIH HHS P30 ES000260
6 · The paper itself

Abstract

Obesity is known to be associated with primary liver cancer (PLC), but the separate effects of excess abdominal and gluteofemoral size are unclear. Thus, we examined the association between waist and hip circumference with risk of PLC overall and by histologic type-hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). The Liver Cancer Pooling Project is a consortium of prospective cohort studies that include data from 1,167,244 individuals (PLC n = 2,208, HCC n = 1,154, ICC n = 335). Multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using proportional hazards regression. Waist circumference, per 5 cm increase, was associated with an 11% increased PLC risk (HR = 1.11, 95%CI: 1.09-1.14), including when adjusted for hip circumference (HR = 1.12, 95%CI: 1.08-1.17) and also when restricted to individuals in a normal body mass index (BMI) range (18.5 to <25 kg/m

Indexed as

AdiposityAdultAgedBile Duct NeoplasmsBody Mass IndexCarcinoma, HepatocellularCholangiocarcinomaFemaleHumansLiver NeoplasmsMaleMiddle AgedProspective StudiesWaist CircumferenceWaist-Hip Ratioabdominal obesityepidemiologygluteofemoral obesityhepatocellular carcinomaintrahepatic cholangiocarcinoma

Identifiers

PMID31677159
PMCPMC7391795
OpenAlexW2985719257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.